Adverse Effect Clinical Trial
Official title:
The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation
Verified date | August 2016 |
Source | General Hospital of Ningxia Medical University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to investigate the efficacy of dezocine pretreatment on dexamethasone 21-phosphate induced perineal irritation (include pian and pruritus).
Status | Completed |
Enrollment | 80 |
Est. completion date | July 2016 |
Est. primary completion date | July 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Aged 18-65 years - ASA physical status I-II - BMI 18-24.5 kg/m2 Exclusion Criteria: - On regular use of analgesic - Contraindication or allergy to steroid or dezocine - Drug or alcohol abuse - Diagnosed with paresthesia or mental diseases - Communication disorders - Pregnancy or nursing |
Country | Name | City | State |
---|---|---|---|
China | General Hospital of Ningxia Medical University | Yinchuan | Ningxia |
Lead Sponsor | Collaborator |
---|---|
General Hospital of Ningxia Medical University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | The duration of perineal irritation after the injection of dexamethasone 21-phosphate among Group D (40 patients receive dezocine 0.1 mg/Kg) and Group C (40 patients receive matching placebo) | In the first 3 min period after the injection of dexamethasone 21-phosphate phosphate | ||
Primary | The occurrence of perineal irritation after the injection of dexamethasone 21-phosphate among Group D (40 patients receive dezocine 0.1 mg/Kg) and Group C (40 patients receive matching placebo) | In the first 3 min period after the injection of dexamethasone 21-phosphate phosphate | ||
Secondary | The severity of perineal irritation after the injection of dexamethasone 21-phosphate among Group D (40 patients receive dezocine 0.1 mg/Kg) and Group C (40 patients receive matching placebo) | In the first 3 min period after the injection of dexamethasone 21-phosphate phosphate |
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