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Clinical Trial Summary

A Phase 1b/2 Study of Repotrectinib in Combination with Other Anticancer Therapies for the Treatment of Subjects with KRAS-Mutant Advanced Solid Tumors (TRIDENT-2)


Clinical Trial Description

Phase 1 Dose Escalation: To evaluate tolerability of repotrectinib at increasing dose levels in combination with other anticancer therapies for the treatment of subjects with locally advanced or metastatic KRAS-mutant solid tumors Phase 2 Efficacy Evaluation: Investigate the anti-tumor efficacy and safety of repotrectinib in combination with other anticancer therapies for the treatment of patients with locally advanced or metastatic KRAS-mutant solid tumors. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05071183
Study type Interventional
Source Turning Point Therapeutics, Inc.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date September 23, 2021
Completion date March 1, 2023

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