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Clinical Trial Summary

This study is a Phase I/II, open-label, dose escalation, and cohort expansion study designed to characterize the safety, tolerability, pharmacokinetic (PK), pharmacodynamics (PD), immunogenicity, and preliminary antitumor activity of ZL-1211 administered by IV infusion on a every 2 weeks (Q2W) schedule.


Clinical Trial Description

The study consists of two stages, Phase I -Dose Escalation Phase to determine the maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of ZL-1211, and Phase II -Cohort Expansion Phase to further define the safety and initial antitumor activity of ZL-1211 with the dose established in the Dose Escalation Phase. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05065710
Study type Interventional
Source Zai Lab (Hong Kong), Ltd.
Contact Zai Biopharmaceutical (Suzhou) Co., Ltd.
Phone +862161632588
Email [email protected]
Status Recruiting
Phase Phase 1/Phase 2
Start date September 30, 2021
Completion date July 30, 2024

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