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Clinical Trial Summary

The primary purpose of this study is to assess the safety and tolerability of RP-6306 in patients with eligible advanced solid tumors, determine the maximum tolerated dose (MTD) and assess preliminary anti-tumor activity.

Clinical Trial Description

Phase 1, multi-center, open-label, dose-escalation study to: - Evaluate the safety profile and MTD of RP-6306 when administered orally to establish the recommended Phase 2 dose and schedule - Characterize the PK and pharmacodynamics of RP-6306 monotherapy - Assess preliminary anti-tumor activity associated with RP-6306 monotherapy ;

Study Design

Related Conditions & MeSH terms

NCT number NCT04855656
Study type Interventional
Source Repare Therapeutics
Contact Peter Manley, MD
Phone 857-322-5553
Email [email protected]
Status Not yet recruiting
Phase Phase 1
Start date April 2021
Completion date June 2023

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