Advanced Rectal Cancers Clinical Trial
Official title:
Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers: Phase 2 Study (RADICAL)
Hypothesis : Therapeutic intensification by increasing the dose delivered to the tumor by
RCMI (conformational radiotherapy by intensity modulation) in order to reduce local relapse,
often associated with poor prognosis
Primary objective: evaluate the rate of tumor sterilization and the toxicities of RTCT with
concomitant boost in intensity modulation in patients with rectal cancer CT3-T4 and / or
cN1-2.
n/a