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Clinical Trial Summary

The efficacy of advanced pancreatic cancer and gastric cancer needs to be further improved. Claudin is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in gastric cancer and pancreatic cancer. Preclinical studies suggest that Claudin18.2CAR-T can effectively improve the remission rate of patients with advanced solid tumors.


Clinical Trial Description

The efficacy of advanced pancreatic cancer and gastric cancer needs to be further improved. Claudin is a kind of integrin membrane protein in the tight junction between epithelium and endothelium, which is highly expressed in gastric cancer and pancreatic cancer. Preclinical studies suggest that Claudin18.2CAR-T can effectively improve the remission rate of patients with advanced solid tumors. Investigators aim to testify to the safety and efficacy of Claudin18.2CAR-T cells in advanced pancreatic cancer and gastric cancer. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05620732
Study type Interventional
Source Shenzhen University General Hospital
Contact Li Yu, Dr
Phone +8675521839178
Email liyu@vip.163.com
Status Recruiting
Phase N/A
Start date October 1, 2022
Completion date October 31, 2028

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