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Cryotherapy in Treating Patients With Lung Cancer That Has Spread to the Other Lung or Parts of the Body

Stage IV Non-small Cell Lung Cancer Clinical Trial

Official title:
A Pilot Study of Cryoablation for Patients With Oligometastatic Cancer Involving the Lung

Clinical Trial Summary

This pilot clinical trial studies the side effects of cryotherapy (cryoablation [CA]) in treating patients with lung cancer. Cryotherapy kills cancer cells by freezing them.

Clinical Trial Description

PRIMARY OBJECTIVES:

I. Assess the initial safety of the CA for lung tumors less than or equal to 3.5 cm in size including acute toxicity (30 days).

SECONDARY OBJECTIVES:

I. Estimate local control.

II. To assess physical function for this cohort of patients.

III. To evaluate the impact of treatment on generic and disease-specific quality of life.

IV. To obtain pilot data useful for the design of a subsequent phase II or randomized phase II trial.

V. Evaluate changes in pulmonary function at 3 months.

OUTLINE:

Patients undergo computed tomography (CT)-guided CA

After completion of study treatment, patients are followed up at 1 week and 1, 3, 6, 12, 24, 36, 48, and 60 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01325753
Study type Interventional
Source Wake Forest University Health Sciences
Contact
Status Withdrawn
Phase N/A
Start date March 2011
Completion date March 2017
View Details
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