Advanced Gastric Cancer Clinical Trial
Official title:
Clinical Study on Treatment of Apatinib Mesylate in First-line Maintenance of Advanced Gastric Cancer -- Multicenter, Open, One Arm Exploratory Study
At present, apatinib was approved for the treatment of advanced gastric cancer after second-line or gastroesophageal junction adenocarcinoma, is in the second one, experience of medication, clinical data, no chemotherapy so now intends to carry out 40 cases of small sample exploratory research, in the conventional chemotherapy after the onset, with APA for Nigeria maintenance treatment, with a preliminary understanding of apatinib in first-line advanced gastric cancer to maintain the efficacy and safety of the treatment, and explore the feasibility of anti generate small molecule targeted therapy in advanced gastric cancer vascular pattern.
The incidence of gastric cancer in China is high, and there is no standard first-line
chemotherapy regimen for advanced gastric cancer. Second-line therapy usually involves
first-line treatment, without the use of drugs for combination or monotherapy, and no uniform
treatment. Apatinib approved provides a good solution to this problem, but this study is in
limit of validity standard after all into the row, not very good reaction in clinical
practice for APA imatinib reality in the treatment of advanced gastric cancer. Therefore, it
is necessary to make a prospective product study to understand the gap between clinical
practice and research results. This study can evaluate apatinib in treatment of advanced
gastric or gastroesophageal junction safe and effective parts of adenocarcinoma in clinical
practice, and the specific usage (such as dose and period). The results of this study can
help the future clinical practice specification of apatinib parts for the treatment of
adenocarcinoma with advanced gastric or gastroesophageal reflux, the advanced gastric or
gastroesophageal adenocarcinoma patients with parts get treatment more safe and effective in
the treatment of.
At present, apatinib was approved for the treatment of advanced gastric cancer after
second-line or gastroesophageal junction adenocarcinoma, is in the second one, experience of
medication, clinical data, no chemotherapy so now intends to carry out 40 cases of small
sample exploratory research, in the conventional chemotherapy after the onset, with APA for
Nigeria maintenance treatment, with a preliminary understanding of apatinib in first-line
advanced gastric cancer to maintain the efficacy and safety of the treatment, and explore the
feasibility of anti generate small molecule targeted therapy in advanced gastric cancer
vascular pattern.
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