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Clinical Trial Summary

This pilot study is a prospective, randomized, controlled, open-label trial to assess the feasibility of a randomized controlled trial of sufficient quality that would assess the efficacy and safety of vancomycin adjustments according to Area under the curve/Minimal inhibitory concentration (AUC0-24h/MIC) calculated by the Bayesian approach rather than by a trough dosage. Randomization will be stratified according to infection severity. Approximately 60 subjects meeting all inclusion and no exclusion criteria will be randomized to have pharmacists perform vancomycin dose adjustments with AUC0-24h / MIC calculated by the Bayesian approach versus the trough dosage approach.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04756895
Study type Interventional
Source CR-CSSS Champlain-Charles-Le Moyne
Contact
Status Completed
Phase N/A
Start date March 1, 2021
Completion date August 6, 2021

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