Adult Clinical Trial
Official title:
Vancomycin Dose Adjustments Comparing Trough Levels to The AUC0-24h/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population: A Pilot Study
This pilot study is a prospective, randomized, controlled, open-label trial to assess the feasibility of a randomized controlled trial of sufficient quality that would assess the efficacy and safety of vancomycin adjustments according to Area under the curve/Minimal inhibitory concentration (AUC0-24h/MIC) calculated by the Bayesian approach rather than by a trough dosage. Randomization will be stratified according to infection severity. Approximately 60 subjects meeting all inclusion and no exclusion criteria will be randomized to have pharmacists perform vancomycin dose adjustments with AUC0-24h / MIC calculated by the Bayesian approach versus the trough dosage approach.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06320626 -
Pharmacokinetic-guided Dosing of Emicizumab
|
Phase 4 | |
Recruiting |
NCT05841667 -
Impact of CES1 Genotype on Remimazolam
|
||
Completed |
NCT06355817 -
Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration
|
N/A | |
Not yet recruiting |
NCT01209481 -
Impact of Educational Group Intervention on the Consumption of Fruit and Vegetables
|
N/A | |
Terminated |
NCT01570465 -
Prospective Study on Severe Infections on Acute Myeloid Leukemia (AML) Patients
|
||
Completed |
NCT04169646 -
Prevention and Intervention of Neck Pain in Swiss Office-Workers
|
N/A | |
Not yet recruiting |
NCT01943565 -
Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study
|
Phase 4 | |
Completed |
NCT00519298 -
Study Evaluating Effects of SAM-531 on Sleep Electroencephalogram (EEG) and Quantitative Wake EEG in Healthy Subjects
|
Phase 1 | |
Completed |
NCT03541837 -
Erector Spinae Plane Block and Pain Management in Cardiac Surgery
|
N/A | |
Active, not recruiting |
NCT00809575 -
Quality of Life and Symptoms in Patients With Newly Diagnosed Myelodysplastic Syndromes
|
||
Completed |
NCT06383117 -
Understanding Effects of Calcium on the Gut-Bone Axis
|
N/A | |
Completed |
NCT05012046 -
Effect of 100% Orange Juice on Food Intake and Glycemic Response in Adults
|
N/A | |
Completed |
NCT05597969 -
The Effect of an Application-based Health Intervention (FoodCoach) on Food Purchases in Switzerland
|
N/A | |
Terminated |
NCT01817153 -
Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock.
|
Phase 2/Phase 3 | |
Not yet recruiting |
NCT05123352 -
Investigation of the Gut Microbiota in Acute Myeloid Leukemia Receiving Two Different Induction Therapies
|
||
Not yet recruiting |
NCT03728114 -
Effects of RIC on Cognitive Function and Blood Oxygen Levels in Unacclimatized Adult at High Altitude
|
N/A | |
Completed |
NCT01162863 -
Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation
|
N/A | |
Completed |
NCT05570435 -
Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response
|
N/A | |
Recruiting |
NCT03713931 -
PUMA Implementation 2
|
||
Completed |
NCT04443231 -
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
|