Adult Patient (Over 18 Yr-old) Admitted to the ICU for Acute Peritonitis Clinical Trial
Official title:
Evaluation of the Detection of B D Glucan in Peritonitis Fluid in Intensive Care Unit (ICU) Patients With Peritonitis for the Diagnosis of Fungal Peritonitis, Compared to Routine Microbiology Diagnosis Method. The PERICAND Study
Invasive candidiasis has a high mortality rate, around 40%. Outcome remains tightly linked to
the time of treatment administration. Routine microbiological techniques give results too
lately to allow prompt antifungal therapy initiation (at least 48 hours). It is important to
develop diagnostic tools to initiate antifungal therapy as early as possible.
The B D glucan detection, one of the major components of the candida cell wall, can be useful
for a early diagnosis.
There are several techniques on the market for the detection of glucan. In Europe and
America, the most used is Fungitell (Associated of Cape Cod, Inc).
There is several studies about the use of such kits for fungemia. A number of studies are
reporting evidences of a early diagnosis.
But, in medical literature, there isn't study focused on the detection of B D glucan in
peritoneal fluid for Candida peritonitis diagnosis.
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