Adrenal Gland Metastases Clinical Trial
Official title:
The Use of Adrenalectomy in Patients With Solitary Adrenal Gland Metastases
The adrenal glands are one of the most common organs involved in metastatic disease.
Metastases are the second most common type of adrenal mass, second only to adenomas. It is a
frequent finding during autopsy with a reported rate as high as 27% in patients with known
primary malignancy. Although several studies have found an increased survival in patients
who undergo resection of solitary adrenal metastases the indications for adrenalectomy in
cases of metastatic adrenal tumor remain controversial. Collinson et al reported an
increased survival in patients with melanoma. Median survival was 16 months for patients who
underwent adrenalectomy compared to 5 months for patients with documented adrenal metastases
treated non surgically.
The aim of this study is to compare retrospectively in case and control study, performing
adrenalectomy, open or laparoscopic, versus supportive treatment for patients with solitary
adrenal gland metastases. The investigators will review charts of patients between January
1994 and November 2009 who had adrenal gland metastases. The variables the inevstigators
will compare are mortality, morbidity, primary tumour sites, histological cell type, age,
tumour size, presence of synchronous metastases, mean time from diagnosis of primary tumor
to treatment of adrenal metastases, indication for adrenalectomy, partial versus total
adrenalectomy, suspected versus confirmed metastatic disease.
n/a
Observational Model: Cohort, Time Perspective: Retrospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT06407024 -
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
|
N/A |