Adherence Clinical Trial
Official title:
Predictivity and Evaluation of the Adherence of Ambulatory Patients Treated With a Direct Oral Anticoagulant for Atrial Fibrillation
The rhythm disorders of Atrial Fibrillation (AF) require continuous treatment with anticoagulants to prevent stroke. The introduction of direct oral anticoagulants (DOACs) quickly supplanted the administration of anti-vitamin K (AVK) which presented an elevated risk of hemorrhage. However, the adherence of the treatments by the OAD is very poor, several studies show that 30 to 50% of the patients fail to adhere to their treatment very soon after starting it. In a recent study, in the United States, using data collected between 2010 and 2014 in more than 60,000 patients with AF, Yao et al show that less than 50% of patients can be considered "adherent". They conclude in this study that adherence to anticoagulation is low in practice, although it may be slightly improved with DOACs. More recently a meta-analysis shows that 66% of patient treated by DOACs were considered adherent (PDC > 80 %). In addition, therapeutic adherence seems to be essential in patients with a CHA2DS2-VASc score ≥2. Indeed improving adherence reduces the risk of stroke occurrence. The investigators propose to evaluate during an interview in the pharmacy, the adherence of ambulatory patients (at the time of their renewal of treatment at the pharmacy) by the "Proportion of Days Covered" (PDC) of the treatment by AOD, and by a simplified questionnaire and to define a profile of patients treated for AF at risk of nonadherence to AOD (PDC adherence prediction score). The investigators perform an observational, prospective multicenter study , in which patients adherence will be quantified in a standardized method.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02858050 -
Portal-724 MEMS for Medication Adherence Patients Taking HCV Medications
|
||
| Completed |
NCT01957865 -
Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
|
N/A | |
| Completed |
NCT02041390 -
Effect of Short Message Service Intervention on Stent Removal/Exchange Adherence in Patients With Benign Pancreaticobiliary Diseases
|
N/A | |
| Completed |
NCT01696331 -
Text Messaging for Adherence in Adolescent Liver Transplant Recipients
|
N/A | |
| Completed |
NCT00218452 -
Smoking Cessation for Young Adults Who Binge Drink - 1
|
Phase 0 | |
| Recruiting |
NCT06351007 -
Educational Program on Dietary Adherence and Nutritional Knowledge in Chronic Kidney Disease Patients (EPAK)
|
N/A | |
| Completed |
NCT02336334 -
Evaluation of Posturing-Adherence in Patients After Intraocular Surgery
|
N/A | |
| Completed |
NCT02354729 -
Encouraging Allergic Young Adults to Carry Epinephrine
|
N/A | |
| Completed |
NCT02135003 -
Non-enrolment and Non-adherence to HIV Care in a Community-based Program, Rakai, Uganda
|
N/A | |
| Recruiting |
NCT02621008 -
Mobile Phone-based Intervention for Promoting Healthy Habits and Weight Loss
|
N/A | |
| Completed |
NCT01247181 -
Cameroon Mobile Phone SMS Trial
|
N/A | |
| Recruiting |
NCT05369845 -
Observance of Continuous Positive Pressure for the Treatment of Obstructive Sleep Apnea Syndrome
|
N/A | |
| Completed |
NCT02424786 -
Non-adherence and Polypharmacy in Elderly Patients
|
N/A | |
| Completed |
NCT01118767 -
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
|
N/A | |
| Active, not recruiting |
NCT03142256 -
3Ps for Prevention Study (Perception, Partners, Pills)
|
Phase 4 | |
| Withdrawn |
NCT02468544 -
Development and Feasibility Testing of a Mobile Phone-Based HIV Primary Care Engagement Intervention
|
N/A | |
| Active, not recruiting |
NCT01509014 -
Community Pharmacy Assisting in Total Cardiovascular Health
|
N/A | |
| Recruiting |
NCT04557293 -
Effort-based Decision-making and CPAPadherence
|
N/A | |
| Terminated |
NCT02822755 -
Home Exercise Adherence in Physical Therapy
|
N/A | |
| Completed |
NCT01120704 -
Evaluation of Treatments to Improve Smoking Cessation Medication Adherence
|
Phase 4 |