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ADHD clinical trials

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NCT ID: NCT04283604 Recruiting - ADHD Clinical Trials

The Effects of a Single Dose of Methylphenidate on Motor Performance

Start date: May 27, 2021
Phase: Phase 4
Study type: Interventional

Aim: To evaluate the effects of MPH on young adults diagnosed with ADHD on different exercise performance tests. Hypothesis: MPH will have positive effects on motor tests requiring concentration. Methods: 200 healthy physical education students, 100 participants diagnosed with ADHD will serve as the treatment group and 100 non-ADHD diagnosed will serve as a control group. The study will be divided into two sub studies (100 participants each), in which, two motor tests will be evaluated (two agility tests, two motor accuracy tests and balance). All participants will arrive for two sessions, and will perform two motor tests in each session. In the second session, half of the participants with ADHD (25 participants) will undergo another session of the same motor tests with their usual treatment (treatment group) and another half (25 participants) without their treatment (ADHD control group). The non-ADHD control group (50 participants) will perform the second session without medications - to assess a learning effect. Note, the investigators are not planning on giving the medication to the participant, rather he/she will consume their own prescribed MPH by them self. Control treatment for ADHD participants will consist of not taking their medication before the motor test. For evaluation of physiological responses and perception of effort, heart rate, temperature, blood pressure and RPE before and after motor tests, will be measured.

NCT ID: NCT04279652 Recruiting - Exercise Clinical Trials

Exercise in Children Attention Deficit Hyperactivity Disorder

Start date: February 28, 2020
Phase: N/A
Study type: Interventional

Attention Deficit Hyperactivity Disorder (ADHD) is a heterogeneous neurodevelopmental disorder characterized by carelessness, hyperactivity and impulsivity, in which genetic, social and physical factors play an important role. Few studies have revealed the physical activity levels and importance of children with ADHD, but there is no consensus on the components of the physical activity program such as intensity, frequency, and severity. The aim of the present study is to investigate the effect of combined exercise training on motor proficiency, physical fitness and cognitive status in children with ADHD.

NCT ID: NCT04240756 Recruiting - ADHD Clinical Trials

Treating Parents With ADHD and Their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial

TPAC
Start date: August 6, 2020
Phase: Phase 3
Study type: Interventional

This study will compare the effectiveness of combined parental stimulant medication and behavioral parent training (BPT) versus BPT alone on child ADHD-related impairment (primary outcome), child ADHD and externalizing symptoms, time to child stimulant prescription (secondary child outcomes) and parental ADHD impairment, parental ADHD symptoms, parenting, and BPT engagement (parental outcomes/target mechanisms). This study will also assess the care delivery context and develop an implementation approach for treatment of families with a parent with ADHD and a child with elevated ADHD symptoms via telehealth in primary care sites providing pediatric care.

NCT ID: NCT04219280 Recruiting - ADHD Clinical Trials

Evaluating Treatment of ADHD in Children With Down Syndrome

TEAM-DS
Start date: October 2, 2020
Phase: Phase 4
Study type: Interventional

Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher risk of ADHD, rates of stimulant medication treatment are disproportionately low in children with DS+ADHD, even though stimulants are the most efficacious ADHD treatment and are recommended by consensus guidelines for use in children with intellectual disability and ADHD. The investigators propose the first randomized clinical trial (RCT) of stimulant medication in children with DS+ADHD. This RCT may provide evidence regarding the short- and long-term safety and efficacy of stimulant use in children with DS+ADHD, both with and without CHD. All children enrolled in the study will complete a comprehensive assessment battery evaluating ADHD diagnostic criteria, as well as behavioral, cognitive, academic, and functional impairments.

NCT ID: NCT04216186 Recruiting - ADHD Clinical Trials

Role of Coenzyme Q in ADHD in Children

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

Role of Coenzyme Q in ADHD in Children

NCT ID: NCT04144790 Recruiting - ADHD Clinical Trials

Impact of Iron Supplementation Treatment on Brain Iron Concentrations

Start date: September 15, 2022
Phase:
Study type: Observational

The goal of the present study is to provide novel data to evaluate brain iron concentration as a mediator of the association between iron supplementation treatment and improvement in symptoms of ADHD and RLS in children, including PLMS. Twelve participants between the ages of 10 and 15 years will be recruited via Kennedy Krieger Institute's Sleep Disorders Clinic. Eligible participants will be asked to complete, at baseline (pre-iron supplementation treatment) and again at follow-up (post-treatment): 1) a 7 Tesla MRI scan, 2) five consecutive nights of RestEaZeā„¢ monitoring, 3) caregiver-reported (or patient-reported if over the age of 10 years) International Restless Leg Syndrome Scale (IRLSS), and 4) caregiver-reported ADHD Rating Scale-5. The treatment interval will be 3 months.

NCT ID: NCT04082234 Recruiting - ADHD Clinical Trials

Reducing Disparities in Behavioral Health Treatment for Children in Primary Care

PASS
Start date: November 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to address a decisional dilemma faced by health system officials, policy makers, and clinical leaders: "Does it make sense to integrate behavior therapy into primary care practice to treat children with ADHD from low-income settings? More specifically, does integrated care improve access to services and patient-centered outcomes for underserved children with ADHD?" Participants will be randomly assigned to one of two groups: Behavior therapy integrated into primary care (Partnering to Achieve School Success; PASS program) to treatment as usual (TAU) informed by American Academy of Pediatrics (AAP) guidelines for ADHD practice and facilitated by electronic practice supports." Participants will be 300 children (ages 5-11) with ADHD and their caregivers served at Children's Hospital of Philadelphia Care Network Locations (primary care offices). Participants are drawn from primary care locations that serve primarily low-income and racial/ethnic minority population.

NCT ID: NCT03781765 Recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

MPH-ATX
Start date: June 4, 2019
Phase: Phase 4
Study type: Interventional

The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD), on reward systems of the brain using fMRI.

NCT ID: NCT03672266 Recruiting - Alzheimer Disease Clinical Trials

Studies of Brain and Body Interaction

Start date: August 1, 2018
Phase:
Study type: Observational

The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic behaviors (ex. walking, pointing) and while breathing at a slow controlled pace. The investigators aim to study these interactions among a variety of populations, from healthy individuals to those with disorders such as Autism Spectrum Disorder(s), including those who may also have an ADHD (Attention-deficit/hyperactivity disorder) diagnosis, Asperger's Syndrome, Alzheimer's Disease, and/or Fragile X syndrome

NCT ID: NCT03559712 Recruiting - ADHD Clinical Trials

Effectiveness of Collaborative Tele-Mental Health Services for ADHD in Primary Care

ECTSAP
Start date: June 7, 2018
Phase: N/A
Study type: Interventional

Aim and objectives: In this study, our goal is to assess the effectiveness of a collaborative tele-mental health approach for treatment of children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) presenting to primary healthcare centers in Dubai. Our primary aim is: To determine if collaborative tele-mental health program improves the clinical and functional outcomes for children with Attention-deficit/hyperactivity disorder (ADHD) in Dubai Secondary aims: 1. To improve the ability of primary health-care providers to diagnose and treat pediatric ADHD, leading to enhanced community capacity, improving patient access and ensuring sustainability. 2. To enhance parent and child satisfaction with the ADHD assessment and treatment process in Dubai.