Step Down Colon Cancer Risk

Status Terminated

Clinical Trial Summary

Hypothesis 1: Exercise will decrease serum markers in a dose response manner.

Hypothesis 2: Participants in the 60 minute intervention will have significantly higher physical activity levels than those in the 30 minute intervention at three months.

Clinical Trial Description

Primary Aim: To conduct a dose response pilot trial of low (30 min/day) or high (60 min/day) dose exercise in men and women at increased risk of colon cancer. The major outcomes are changes in serum levels of four risk-related biomarkers: insulin, C-peptide, IL-6 and PGE-2.

Secondary Aim. To compare changes in the secondary outcome of physical activity over three months. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Adenomatous Polyps

Clinical Trial Details

NCT number	NCT01476631
Study type	Interventional
Source	Washington University School of Medicine
Contact
Status	Terminated
Phase	N/A
Start date	November 2008
Completion date	April 2010

View Details

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