Influenza, Human Clinical Trial
Official title:
Double Blind Randomised Placebo Controlled Trial for Evaluation of Efficacy and Safety of Ingavirin® for Post-exposure Profilaxis During Rise in the Incidence of Influenza and Other Acute Respiratory Viral Infections in Adults
The purpose of the study was to evaluate efficacy of prophylactic Ingavirin intake by people having contact with sick people infected with influenza and other acute respiratory viral infections
The study includes 7 days of treatment period and 30 days of follow-up, 37 days total.
The participant was receiving Ingavirin or placebo for 7 days. Then during 30 days the
participant was under supervision.
Visits were performed at days 2-7 (every day) since inclusion and then every 5 days during
follow-up period.
Wherever during the study the participant developed symptoms of flu or other acute
respiratory viral infection, the participant was taken for medical care to observe his
condition, symptoms dynamics, lab tests, including laboratory verification of viral origin
of the disease. Medical care was established for 10±2 days since symptoms. Everyday for 3
days and additional visits for 5±1 and 10±2 days of the disease.
The patient had the required symptomatic treatment, additionally the patient could be
institutionalised if necessary.
Wherever the participant developed symptoms during treatment period, the patient was taken
investigational drug on schedule.
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