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Combined Epidural Morphine and Midazolam on Postoperative Pain

Acute Postoperative Pain Clinical Trial

Official title:
Effect of Epidural Morphine and Midazolam on Postoperative Painin Patients Undergoing Major Abdominal Cancer Surgery

Clinical Trial Summary

this study aim to Compare the effect of preoperative Epidural Midazolam, Morphine and their combination in postoperative pain relief and total morphine consumption.

Clinical Trial Description

Major abdominal surgeries with abdominal incisions lead to severe abdominal pain, which if treated inadequately, can cause shallow breathing, atelectasis, retention of secretions and lack of cooperation in physiotherapy. This increases the incidence of post-operative morbidity and leads to delayed recovery.Epidural anesthesia is safe and inexpensive technique with the advantage of providing surgical anesthesia and prolonged postoperative pain relief. It also an effective treatment of operative pain blunts autonomic, somatic and endocrine responses. Morphine and midazolam can be used as adjuvant to bupivicain to reduced the postoperative pain ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04033471
Study type Interventional
Source Assiut University
Contact Shereen M Kamal, Associate proferssor
Phone 01006279209
Email sheridouh79@yahoo.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 1, 2019
Completion date April 2021
View Details
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