View clinical trials related to Acute Post-thoracotomy Pain.
Filter by:To validate the efficacy of miniaturized ultrasound needle transducer as the primary guide for thoracic regional anesthesia.
The investigators aim to determine whether ultrasound-guided preemptive paravertebral blockade (PVB) local anaesthetic (pre-PVB LA), administered in addition to the post-operative PVB (post-PVB) local anaesthetic (LA) infusion, reduces acute postoperative pain, opioid requirement, chronic pain, and improves surgical recovery, in thoracoscopic surgery for lung cancer.
The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.
This study evaluates the effect of adding dexmedetomidine as an adjuvant to bupivacaine in patients undergoing thoracotomy when administered peri-neurally in thoracic paravertebral space.
Postoperative thoracotomy pain is normally managed with an epidural catheter and continuous epidural analgesia (CEA). However, for some surgical procedures, patient controlled epidural anesthesia (PCEA) is more effective but little research has compared the two methods following thoracotomy. The current randomized, prospective clinical investigation did just this. Following institutional ethics approval 47 patients scheduled for thoracotomy were recruited for this prospective, randomized, unblinded study. A thoracic epidural catheter was sited preoperatively. Postoperatively patients were randomized to receive epidural infusions (hydromorphone 10 mcg/mL + bupivacaine 1 mg/mL) for 48 hours postoperatively via PCEA (n= 24) or CEA (n=23). CEA infusion rates were titrated to achieve pain scores ≤ 3 out of 10 (numeric rating scale (NRS)) in the recovery room. PCEA parameters were adjusted to allow an equivalent dose per hour. The primary outcome was consumption of local anaesthetic/opioid. The secondary outcomes were worst pain and pain while coughing (0-10 NRS).