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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06077188
Other study ID # Thirstgum
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date December 1, 2023
Est. completion date March 1, 2024

Study information

Verified date February 2024
Source TC Erciyes University
Contact ÖZLEM CEYHAN
Phone +903520207 6666
Email ozlemg@erciyes.edu.tr
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Nausea and vomiting are one of the most common symptoms in acute pancreatitis. In addition to pharmacological methods for nausea and vomiting, non-pharmacological methods can also be used. Among these, anticipatory nausea and vomiting can be prevented by behaviors aimed at distracting attention. This study will be conducted to evaluate the effect of chewing gum on the severity of nausea-vomiting and thirst in patients with acute pancreatitis. The study will be conducted with a total of 60 patients, 30 intervention and 30 control. Patients in the intervention group will chew xylitol gum five times a day for three days. The patients' thirst and nausea and vomiting conditions will be examined.


Recruitment information / eligibility

Status Recruiting
Enrollment 60
Est. completion date March 1, 2024
Est. primary completion date February 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Those diagnosed with acute pancreatitis, - Without total dental prosthesis, - Without salivary gland infection, - Those who have not had salivary gland surgery, - No difficulty in chewing, - Not receiving oxygen therapy, - Able to answer all questions and be communicativ Exclusion Criteria: - Those with diabetes, - Does not like chewing gum, - Receiving radiotherapy or chemotherapy,

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Gum group
Group chewing gum with xylitol

Locations

Country Name City State
Turkey Erciyes University Hospital Kayseri

Sponsors (1)

Lead Sponsor Collaborator
TC Erciyes University

Country where clinical trial is conducted

Turkey, 

References & Publications (4)

Honarmand M, Farhad-Mollashahi L, Nakhaee A, Sargolzaie F. Oral manifestation and salivary changes in renal patients undergoing hemodialysis. J Clin Exp Dent. 2017 Feb 1;9(2):e207-e210. doi: 10.4317/jced.53215. eCollection 2017 Feb. — View Citation

Jensdottir T, Buchwald C, Nauntofte B, Hansen HS, Bardow A. Saliva in relation to dental erosion before and after radiotherapy. Acta Odontol Scand. 2013 May-Jul;71(3-4):1008-13. doi: 10.3109/00016357.2012.741704. Epub 2012 Nov 21. — View Citation

Oyetola EO, Owotade FJ, Agbelusi GA, Fatusi OA, Sanusi AA. Oral findings in chronic kidney disease: implications for management in developing countries. BMC Oral Health. 2015 Feb 20;15:24. doi: 10.1186/s12903-015-0004-z. — View Citation

Silva AC, Aprile LR, Dantas RO. EFFECT OF GUM CHEWING ON AIR SWALLOWING, SALIVA SWALLOWING AND BELCHING. Arq Gastroenterol. 2015 Jul-Sep;52(3):190-4. doi: 10.1590/S0004-28032015000300007. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Thirst Severity -Visual Analog Scale Visual Analog Scale is a 10 cm long scale that evaluates the severity of thirst. Apply in the morning of the 1st day after application
Secondary Rhodes Nausea, Vomiting and Retching Index It is an eight-item scale that measures the number and severity of patients' nausea, vomiting and retching in the last 24 hours. Apply in the morning of the 1st day after application
Secondary Rhodes Nausea, Vomiting and Retching Index ( It is an eight-item scale that measures the number and severity of patients' nausea, vomiting and retching in the last 24 hours. Apply in the morning of the 1st day after application
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