EFFECT OF CHEWING GUM ON CONTROLLING NAUSEA/VOMITING AND THIRST IN PATIENTS WITH ACUTE PANCREATITIS

Acute Pancreatitis Clinical Trial

Official title:

Erciyes University

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06077188
• Other study ID #: Thirstgum
• Status: Recruiting
• Phase: N/A
• Start date: December 1, 2023
• Est. completion date: March 1, 2024

Study information

• Verified date: February 2024
• Source: TC Erciyes University
• Contact: ÖZLEM CEYHAN
• Phone: +903520207 6666
• Email: ozlemg[@]erciyes.edu.tr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Nausea and vomiting are one of the most common symptoms in acute pancreatitis. In addition to pharmacological methods for nausea and vomiting, non-pharmacological methods can also be used. Among these, anticipatory nausea and vomiting can be prevented by behaviors aimed at distracting attention. This study will be conducted to evaluate the effect of chewing gum on the severity of nausea-vomiting and thirst in patients with acute pancreatitis. The study will be conducted with a total of 60 patients, 30 intervention and 30 control. Patients in the intervention group will chew xylitol gum five times a day for three days. The patients' thirst and nausea and vomiting conditions will be examined.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: March 1, 2024
• Est. primary completion date: February 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Those diagnosed with acute pancreatitis,
• Without total dental prosthesis,
• Without salivary gland infection,
• Those who have not had salivary gland surgery,
• No difficulty in chewing,
• Not receiving oxygen therapy,
• Able to answer all questions and be communicativ

Exclusion Criteria:

• Those with diabetes,
• Does not like chewing gum,
• Receiving radiotherapy or chemotherapy,

Related Conditions & MeSH terms

• Acute Pancreatitis
• Pancreatitis
• Thirst

Intervention

Other:
• Gum group
Group chewing gum with xylitol

Locations

Country	Name	City	State
Turkey	Erciyes University Hospital	Kayseri

Sponsors (1)

Lead Sponsor	Collaborator
TC Erciyes University

Country where clinical trial is conducted

Turkey, 

References & Publications (4)

Honarmand M, Farhad-Mollashahi L, Nakhaee A, Sargolzaie F. Oral manifestation and salivary changes in renal patients undergoing hemodialysis. J Clin Exp Dent. 2017 Feb 1;9(2):e207-e210. doi: 10.4317/jced.53215. eCollection 2017 Feb. — View Citation

Jensdottir T, Buchwald C, Nauntofte B, Hansen HS, Bardow A. Saliva in relation to dental erosion before and after radiotherapy. Acta Odontol Scand. 2013 May-Jul;71(3-4):1008-13. doi: 10.3109/00016357.2012.741704. Epub 2012 Nov 21. — View Citation

Oyetola EO, Owotade FJ, Agbelusi GA, Fatusi OA, Sanusi AA. Oral findings in chronic kidney disease: implications for management in developing countries. BMC Oral Health. 2015 Feb 20;15:24. doi: 10.1186/s12903-015-0004-z. — View Citation

Silva AC, Aprile LR, Dantas RO. EFFECT OF GUM CHEWING ON AIR SWALLOWING, SALIVA SWALLOWING AND BELCHING. Arq Gastroenterol. 2015 Jul-Sep;52(3):190-4. doi: 10.1590/S0004-28032015000300007. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Thirst Severity -Visual Analog Scale	Visual Analog Scale is a 10 cm long scale that evaluates the severity of thirst.	Apply in the morning of the 1st day after application
Secondary	Rhodes Nausea, Vomiting and Retching Index	It is an eight-item scale that measures the number and severity of patients' nausea, vomiting and retching in the last 24 hours.	Apply in the morning of the 1st day after application
Secondary	Rhodes Nausea, Vomiting and Retching Index (	It is an eight-item scale that measures the number and severity of patients' nausea, vomiting and retching in the last 24 hours.	Apply in the morning of the 1st day after application