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Fecal Microbiota Transplantation for Pancreatitis With Infectious Complications(FMTPIC)

Acute Pancreatitis Clinical Trial

Official title:
Fecal Microbiota Transplantation in SAP（Severe Acute Pancreatitis）Patients With Infectious Complications

Clinical Trial Summary

Infectious complications are responsible for most of deaths in acute pancreatitis.Intestinal barrier dysfunction and increased intestinal permeability was associated with bacterial translocation which is believed to prompted these infections.The purpose of this clinical trail is to observe the potential capability of FMT in reduce the bacterial translocation and alleviate infectious complications by the reconstruction of a gut functional state.

Clinical Trial Description

Investigators aims to restore the intestinal bacteria homeostasis through FMT by retention enema with fresh bacteria,thus minimizing bacterial translocation and alleviating infectious complications. The investigators will further examine the effect of FMT on the incidence of infectious complications，duration of clinical course and mortality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02318147
Study type Interventional
Source The First Affiliated Hospital of Nanchang University
Contact Yin Zhu, MD
Phone 13970841464
Email zhuyin27@sina.com
Status Recruiting
Phase Phase 1
Start date November 2016
Completion date December 2018
View Details
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