Sub-dissociative Dose Ketamine Dosing Study

Status Completed

Clinical Trial Summary

Goal is to determine if in adults presenting to the Emergency Department (ED) with moderate to severe acute pain, Ketamine administered at 0.15 mg/kg will provide similar pain relief to Ketamine administered at 0.3 mg/kg, with fewer adverse effects.

Clinical Trial Description

Study investigators will enroll participants who present to the Emergency Department (ED) with moderate to severe acute pain, and require intravenous pain medication. Participants will be double-blinded and randomized to one of the two treatment groups. Investigators aim to determine if ketamine 0.15 mg/kg IVPB is non-inferior to ketamine 0.3 mg/kg IVBP for the treatment of acute moderate to severe pain in the Emergency Department (ED). Study investigators hypothesize that in adults presenting to the ED with moderate to severe acute pain, SDK administered at 0.15 mg/kg will provide similar pain relief to SDK at 0.3 mg/kg, with reduced adverse effects. ;

Study Design

Related Conditions & MeSH terms

Acute Pain

Clinical Trial Details

NCT number	NCT03714620
Study type	Interventional
Source	Loyola University
Contact
Status	Completed
Phase	Phase 4
Start date	October 15, 2018
Completion date	September 17, 2019

View Details

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