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Acute Otitis Media clinical trials

View clinical trials related to Acute Otitis Media.

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NCT ID: NCT02345447 Completed - Acute Otitis Media Clinical Trials

Herbal-Based Medication vs. Placebo in Preventing Acute Otitis Media in Children at High Risk of Recurrence

OTV_PRE_01
Start date: October 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to study whether a herbal-based medication is superior to placebo for prevention of acute otitis media in pre-school children with upper respiratory tract infection.

NCT ID: NCT02297815 Completed - Acute Otitis Media Clinical Trials

Comparative Effectiveness of Antibiotics for Respiratory Infections

CEARI
Start date: January 2014
Phase:
Study type: Observational

The purpose of this study is to identify and use patient centered outcomes to compare narrow-spectrum and broad-spectrum antibiotics for the treatment of common acute respiratory tract infections (ARTIs) in children.

NCT ID: NCT02110732 Completed - Acute Otitis Media Clinical Trials

Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil

Start date: January 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of oral administration of probiotic Lactobacillus rhamnosus GG in middle ear and adenoid tonsil.

NCT ID: NCT02092454 Completed - Pain Clinical Trials

Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis Media

Start date: September 2013
Phase: Phase 2
Study type: Interventional

To assess the clinical safety and efficacy of the Benzocaine relative to placebo in pain relief associated with acute otitis media.

NCT ID: NCT02074007 Terminated - Acute Otitis Media Clinical Trials

Study to Compare Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media (AR01007)

Start date: December 2013
Phase: Phase 3
Study type: Interventional

Children ages 2 months to less than 19 years old, who have been diagnosed with a middle ear infection may receive either medicated ear drops (AR01) or glycerin (placebo) ear drops. The patient or caregiver will measure the amount of ear pain before and after the ear drops to establish if the medicated ear drops decrease the amount of pain more than the placebo ear drops. The subject may leave the clinic 60 minutes after the first dose. The ear drops can be used up to 4 days, as needed for ear pain.

NCT ID: NCT02044341 Completed - Acute Otitis Media Clinical Trials

Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media

AR01006
Start date: December 2013
Phase: Phase 3
Study type: Interventional

Children ages 2 months to less than 19 years old, who have been diagnosed with a middle ear infection may receive either medicated ear drops (AR01) or glycerin (placebo) ear drops. The patient or caregiver will measure the amount of ear pain before and after the ear drops to establish if the medicated ear drops decrease the amount of pain more than the placebo ear drops. The subject may leave the clinic 60 minutes after the first dose. The ear drops can be used up to 4 days, as needed for ear pain.

NCT ID: NCT02037893 Completed - Acute Otitis Media Clinical Trials

Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media

Start date: November 2013
Phase: Phase 2
Study type: Interventional

The primary objective is to compare the effect of treatment with a combination of ear solutions on the reduction of pain symptoms at 1 hour after dosing in children with acute otitis media.

NCT ID: NCT01941381 Completed - Acute Otitis Media Clinical Trials

Does Tympanometry Predict Antibiotic Usage in Acute Otitis Media?

Start date: October 2013
Phase:
Study type: Observational

Due to recent efforts to decrease antibiotic overuse, and reports of high rates of spontaneous resolution for clinically diagnosed Acute Otitis Media(AOM), most physicians now wait 48-72 hours before starting antibiotics for common ear infections. The investigators are interested to see if those patients with documented middle ear effusions, as determined by tympanometry, have higher rates of eventual antibiotic usage than those with normal tympanometry results. If there is a significant disparity between those with a positive tympanogram and those without the investigators may be able to identify a group that will benefit from antibiotics and a group that would not need treatment.

NCT ID: NCT01908803 Terminated - Acute Otitis Media Clinical Trials

Proof-of-Concept Study of a Single Application of an Investigational Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes

Start date: December 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate a single application of AL-60371/AL-817 Otic Suspension relative to ototopical CIPRODEX for sustained clinical cure, microbiological success, and time to cessation of otorrhea.

NCT ID: NCT01800747 Completed - Acute Otitis Media Clinical Trials

Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics)

DAP
Start date: June 2012
Phase: Phase 4
Study type: Interventional

The general hypothesis is that delayed antibiotic treatment strategy present similar effectiveness, when compared with non-prescription of antibiotics or the prescription of antibiotics, in the non-complicated acute respiratory tract infections in pediatric patients.