Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Acute Myocardial Infarction Clinical Trial

Official title:

Evaluation of the Methods and Management of Acute Coronary Events: 3. Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01808027
• Other study ID #: 10/H1313/74
• Status: Completed
• Phase: N/A
• First received: March 7, 2013
• Last updated: March 7, 2013
• Start date: February 2011
• Est. completion date: February 2013

Study information

• Verified date: March 2013
• Source: University of Leeds
• Contact: n/a
• Is FDA regulated: No
• Health authority: United Kingdom: National Institute for Health Research
• Study type: Observational [Patient Registry]

Clinical Trial Summary

To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.

Description:

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depends upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation and whether patients take their medication after discharge from hospital. Using powerful statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5555
• Est. completion date: February 2013
• Est. primary completion date: February 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age > 18 years

• Both sexes

• Acute admission to the acute Trust with suspected acute coronary syndrome

Exclusion Criteria:

• Patients at a terminal stage of any illness

• Those in whom follow up would be inappropriate or impractical

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Acute Myocardial Infarction
• Myocardial Infarction

Locations

Country	Name	City	State
United Kingdom	University of Leeds	Leeds	West Yorkshire

Sponsors (1)

Lead Sponsor	Collaborator
University of Leeds

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Develop a risk score and a near-point risk Acute Coronary Syndrome model	Develop a risk score and a near-point risk Acute Coronary Syndrome model	two years	Yes
Primary	delays to treatment	Quantification of hospital attributable effects relating to early and late mortality	12 months	Yes
Secondary	Describing trajectories of quality of life recovery patterns	Describing trajectories of quality of life recovery patterns	12 month	Yes