Acute Myeloid Leukemia Clinical Trial
Official title:
Rôle Pronostique Des métabolismes du Stress Oxydatif et du Fer Dans Les Leucémies Aiguës Myéloblastiques
In this study, the investigators study the prognostic role of oxidative stress metabolism and iron in Acute myeloid leukemia.
Primary goal of this study is to Evaluate the characteristics of regulatory networks of iron
and redox balance in leukemic cells, to study the correlations between the prognosis of AML
patients (in terms of response to induction chemotherapy and survival i) and metabolism of
these markers. Secondary ones areto assess the impact of induction therapy on markers of
oxidative stress and to correlate biological iron and redox metabolism with the molecular
status of patients (eg Flt3/IDH/CEBPA/NPM...).
Eligibility criteria are patients at diagnostic of de novo acute myeloid leukemia
(promyelocytic excluded) aged from 18 to 100 years.
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Observational Model: Cohort, Time Perspective: Prospective
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