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Clinical Trial Summary

This is a multi-center, randomized, trial to evaluate the efficacy of adding crenolanib to salvage chemotherapy versus salvage chemotherapy alone in subjects with relapsed/refractory FLT3-mutant AML. Approximately 320 subjects will be randomized 1:1 to receive either salvage chemotherapy (HAM or FLAG-Ida) with crenolanib (treatment arm 1) or salvage chemotherapy (HAM or FLAG-Ida) alone (treatment arm 2).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03116477
Study type Interventional
Source Arog Pharmaceuticals, Inc.
Contact VArtika Agarwal
Email vagarwal@davacro.com
Status Not yet recruiting
Phase Phase 3
Start date August 2017
Completion date August 2020

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