Drug Combination on Exercise Performance at High Altitude

Status Completed

Clinical Trial Summary

This study is being conducted to determine the effectiveness of using two FDA approved medications in concert to reduce the likelihood of sickness due to low oxygen levels and to reduce the decrement in physical performance at higher elevations. The investigators hypothesize that this drug combination will reduce the symptoms of acute mountain sickness and improve exercise performance at high altitude compared to placebo.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator)

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01902758
Study type	Interventional
Source	University of Montana
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	August 2013
Completion date	August 2013

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04111263` - Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude	N/A
Completed	`NCT01842906` - Study Looking at End Expiratory Pressure for Altitude Illness Decrease (SLEEP-AID)	N/A
Completed	`NCT01536288` - Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness	Phase 2
Completed	`NCT00326703` - Effects of Aircraft Cabin Altitude on Passenger Comfort and Discomfort	N/A
Completed	`NCT06310642` - Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness	Phase 4
Not yet recruiting	`NCT06393998` - CO2 Supplement for Treatment of Acute Mountain Sickness	N/A
Completed	`NCT03561675` - Effect of Acetazolamide on Acute Mountain Sickness in Lowlanders Older Than 40 Years	Phase 4
Completed	`NCT00559832` - Prevention of Acute Mountain Sickness by Intermittent Hypoxia	N/A
Completed	`NCT01436383` - Oxidative Stress in Hypobaric Hypoxia	N/A
Completed	`NCT00603122` - Acclimatization Mechanisms During Ascent to 7500m	N/A
Completed	`NCT00627965` - Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness	Phase 4
Completed	`NCT00664001` - Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness	Phase 3
Not yet recruiting	`NCT06145113` - The Effect of Continuous Positive Pressure Ventilation on Symptoms of Acute Mountain Sickness	N/A
Recruiting	`NCT05733338` - The Effects of Intermittent Hypoxia on Acute Hypoxic Injury	N/A
Completed	`NCT01522326` - Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness	N/A
Completed	`NCT03270787` - Study of Compound Danshen Dripping Pills to Treat Acute Mountain Sickness	Phase 1/Phase 2
Completed	`NCT02811016` - Inhaled Budesonide and Acute Mountain Sickness	Phase 1
Recruiting	`NCT00886912` - Training in Hypoxia to Prevent Acute Mountain Sickness	N/A
Terminated	`NCT03956472` - Alternative Treatments in Acute Mountain Sickness	N/A
Recruiting	`NCT03621410` - T89 in Prevention and Treatment of Acute Mountain Sickness (AMS) During Rapid Ascent	Phase 2