Acute Kidney Attack in Severe Traumatized Patients

Acute Kidney Injury Clinical Trial

— NEPHROTRAUMA  

Official title:

Evaluation of the Incidence of Acute Kidney Attack by Dosing Nephrocheck® in Severe Traumatized Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03877978
• Other study ID #: 69HCL18_0903
• Status: Completed
• Start date: May 16, 2019
• Est. completion date: December 2, 2021

Study information

• Verified date: May 2022
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute Kidney Injury (AKI) is a common complication of severe traumatized patients. The diagnosis is often delayed. The Nephrocheck® test allows an earlier assessment of renal stress. The objective of our study is to determine the incidence of risk of AKI in severe traumatized patients within the first 24 hours after their admission to our trauma center. The risk of AKI is defined by a NephroCheck® test >0.3

Recruitment information / eligibility

• Status: Completed
• Enrollment: 196
• Est. completion date: December 2, 2021
• Est. primary completion date: December 2, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age >18 years

• trauma patients with ISS =15

• patient admitted to the resuscitation bay of Edouard Herriot Hospital

Exclusion Criteria:

• anuric patient

• opposition of the patient (or a trusted person) to participate

• pregnant or lactating woman

• age <18 years

Related Conditions & MeSH terms

• Acute Kidney Injury

Intervention

Biological:
• Nephrocheck test
Nephrocheck® measurement on urine sample at different timepoints.

Locations

Country	Name	City	State
France	Hôpital Edouard Herriot	Lyon

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of patients with Nephrocheck score > 0,3	Incidence of severe traumatized patient at risk of AKI as defined by Nephrocheck test score > 0,3 within the first 24 hours after admission	Up to 24 hours after trauma