Korean Cohort Study of AKI & HRS in Cirrhosis

Status Recruiting

Clinical Trial Summary

The aim of this study is to investigate i) whether two biomarkers (urine NAG, urinary cystatin C) could be predictive factor in patient with liver cirrhosis, , and ii) whether these biomarkers can predict response of terlipressin.

Clinical Trial Description

Acute kidney injury (AKI) in patients with liver cirrhosis is sometimes accompanied by tubular injury which can lead to poor outcome. Current AKI criteria using serum creatinine (Cr) has some limitations to predict reversibility of renal function and discriminate renal parenchymal injury in cirrhotic patients. The aim of this study is to evaluate whether urine biomarkers [cystatin C, N-acetyl-β-D-Glucosaminidase (NAG)] can predict survival and response to terlipressin in cirrhotic patients with AKI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03530761
Study type	Observational [Patient Registry]
Source	Soonchunhyang University Hospital
Contact	Jeong-Ju Yoo, Doctor
Phone	82-10-9676-3128
Email	puby17@naver.com
Status	Recruiting
Phase
Start date	August 1, 2017
Completion date	December 31, 2019

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