Acute Kidney Injury Clinical Trial
Official title:
Clinical Study of Renal Resistive Index and Hemodynamic Parameters Changes Caused by Fluid Resuscitation to Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients
Record the renal resistive index and hemodynamic parameters ( record the cardiac output and stroke volume if the patient's next to kin agree to undertake a PiCCO monitoring ) before and after resuscitation for severe sepsis or septic shock patients, to determine whether the changes of resistive index or hemodynamic parameters, especially the cardiac output can be a better parameter to predict AKI
- Purpose: To examine whether the resuscitation-induced changes of renal resistive index
or hemodynamic parameters has the superiority as a valid tool to evaluate the renal
perfusion improvement and whether the changes can better predict AKI occurrence in
severe sepsis or septic shock patients.
- Methods: Measure the renal resistive index and take record of hemodynamic parameters
(use a PiCCO monitoring to measure cardiac output if the patient's next to kin agree to
undertake such a catheter ) before and after successful resuscitation for severe sepsis
or septic shock patients, followup to determine the occurrence of AKI and mortality.
- Hypothesis: The changes of resistive index or cardiac output during shock resuscitation
may be a better parameter to evaluate renal perfusion and predict AKI, and may have a
better value to guide renal protective therapy in septic shock.
;
Observational Model: Cohort, Time Perspective: Prospective
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