Acute Ischaemic Stroke Clinical Trial
Official title:
Effect of Combined Anodal tDCS and Peripheral Nerve Stimulation on Motor Recovery in Acute Stroke
Recent work showed that application of peripheral nerve and cortical stimulation
independently can induce 10-15 % improvement in motor performance in patients with chronic
stroke.
The purpose of this study was to compare in post-stroke hemiplegic patients the effect on
motor recovery of one session of anodal transcranial direct current stimulation to the
ipsilesional primary motor cortex (M1) combined with a peripheral radial nerve electrical
stimulation (rEPNS) to the paretic hand repeated 5 successive days with the effect of the
same peripheral nerve stimulation combined with sham tDCS.
Design: randomized, double-blind, parallel controlled clinical trial. Patients eligible for
the study: Acute ischaemic stroke Primary outcome measure: Jebsen Taylor test Secondary
outcome measures Nine peg hole test Hand tapping grip and wrist force Cortical excitability
of Ipsilesional M1(TMS) Follow-up: 30 days
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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