Efficacy of Lactose-free Milk in Treating Acute Gastroenteritis in Infants

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine whether lactose-free milk will change diarrhea duration and severity in formula-fed infants with acute gastroenteritis presenting to pediatric wards.

Clinical Trial Description

More than 525 000 children die each year due to diarrheal disease, the second leading cause of death among children under five. Children from Asian countries, including Vietnamese children, frequently have lactose intolerance. In addition, gastroenteritis, specifically rotavirus-induced gastroenteritis, temporarily impairs lactase enzymes in the intestines. In a recent Cochrane review of 33 randomized and quasi-randomized trials, lactose-free diets reduced diarrhea among children younger than 5 years old. These trials, however, involved inpatients in middle-or high-income countries. Neither patient was from a developing country, where diarrheal diseases often cause significant morbidity and mortality. The purpose of this study is to determine whether lactose-free milk will change the duration and severity of diarrhea in Vietnamese infants with acute gastroenteritis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05634603
Study type	Interventional
Source	The Women and Children Hospital of An Giang
Contact
Status	Recruiting
Phase	N/A
Start date	December 1, 2022
Completion date	April 30, 2025

View Details

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