Acute Gastroenteritis Clinical Trial
Official title:
Gelatin Tannate as Treatment for Acute Childhood Gastroenteritis: a Prospective, Randomized, Single-blind Controlled Clinical Trial
Oral rehydration therapy is the only treatment recommended by the World Health Organization
in acute diarrhea in children. The aim of this study was to compare the efficacy and safety
of a therapy with gelatin tannate plus oral rehydration versus oral rehydration alone in
children with acute gastroenteritis.
This is a single-blind, prospective, randomized and parallel study performed in two
Pediatric Services of tertiary referral hospitals. Patients, ages 3 to 36 months with acute
gastroenteritis randomized to receive an oral rehydration solution (OR), or an oral
rehydration solution plus gelatin tannate (OR+G). The primary outcomes evaluated were: the
number of bowel movements after 48 and 72 hours after initiating treatments. Secondary
outcomes were: duration of diarrhea (days), stool characteristics and adverse events. Other
clinical variables, as weight, fever, vomiting, appetite and the acceptability of the two
treatments were also recorded.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04682860 -
Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide
|
Phase 4 | |
| Recruiting |
NCT03851835 -
Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis
|
Phase 3 | |
| Completed |
NCT01577043 -
Efficacy of Racecadotril in Acute Watery Diarrhea in Children
|
Phase 4 | |
| Completed |
NCT03234777 -
Evaluating a Knowledge Translation Tool for Parents
|
N/A | |
| Not yet recruiting |
NCT02619201 -
Antiemetic Efficacy of Ondansetron Versus Metoclopramide
|
Phase 3 | |
| Completed |
NCT02280759 -
Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children.
|
Phase 1 | |
| Completed |
NCT06090708 -
Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis
|
N/A | |
| Recruiting |
NCT05270291 -
Infectious Etiology of Vomiting in Children With Presumed Acute Gastroenteritis
|
||
| Completed |
NCT02025452 -
Novel Diagnostics and Probiotics to Improve Management of Paediatric Acute Gastroenteritis
|
Phase 4 | |
| Not yet recruiting |
NCT06038305 -
Prevalence of Anemia and Growth Assessment in Acute Gastroenteritis
|
||
| Completed |
NCT02803827 -
Optimizing the Management of Acute Diarrhoeal Disease
|
Phase 3 | |
| Completed |
NCT02174874 -
Ondansetron Oral Versus Orally Disintegrating Tablets (ODT)
|
N/A | |
| Completed |
NCT03539913 -
Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children
|
Phase 4 | |
| Recruiting |
NCT06137014 -
Fortified Oral Rehydration Therapy for Pediatric Diarrhea
|
Phase 1/Phase 2 | |
| Completed |
NCT04463355 -
Video Discharge Instructions for Pediatric Gastroenteritis in an Emergency Department
|
N/A | |
| Completed |
NCT04555200 -
Continuous Enteral Rehydration by Nasogastric Tube With ORS in Children With Acute Gastroenteritis
|
||
| Unknown status |
NCT02177799 -
Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon
|
N/A | |
| Completed |
NCT02169817 -
Evaluation Of Bacillus Clausii In Treatment Of Acute Diarrhea In Latin American Children
|
Phase 4 | |
| Completed |
NCT01886755 -
Efficacy of an Oral Rehydration Solution Containing the Probiotic Lactobacillus Reuteri Protectis and Zinc in Infants With Acute Gastroenteritis
|
N/A | |
| Completed |
NCT01257672 -
Symptomatic Treatment of Acute Gastroenteritis
|
Phase 3 |