Acute Coronary Syndrome (ACS) Clinical Trial
Official title:
Real-TICA Real Life Long-term Adherence to Ticagrelor After PCI for Acute Coronary Syndromes. Evaluation of Antiplatelet Therapy After 12 Months in Patients Undergoing PCI and Treated With Ticagrelor During the Acute Phase of an ACS.
Documentation of long-term data regarding ticagrelor use and evaluation of reasons for discontinuation of ticagrelor in patients with ACS
REAL-TICA is a retrospective non-interventional study to assess the long-term use of
ticagrelor in patients with ACS and to evaluate the reasons for discontinuation of
ticagrelor.
For this purpose, selected sites from the ALKK-PCI registry and the respective patients will
be identified. The sites' eligibility for this study includes the frequent use of ticagrelor
during the acute phase of ACS. Eligible patients are characterised by the diagnosis of ACS
and the use of ticagrelor during PCI.
The eligible sites will be contacted by IHF and asked to contact their eligible patients by
letter to obtain informed consent of the patients for the planned 12M follow-up by IHF. A
detailed questionnaire on events within the last 12 months, current symptoms, current
medication and the use of ticagrelor will be added to the patients' letters. Patients then
are asked to return their responses on consent to participate in the study as well as the
filled in questionnaire to IHF. Alternatively, patients may choose to receive a telephone
call by IHF to answer the detailed questionnaire in person. In case of essential information
missing, IHF will contact the primary care physician of the patient directly to obtain
information about clinical events and medications.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT00385138 -
Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition.
|
Phase 3 | |
| Completed |
NCT01944800 -
Prospective, Randomized Trial of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome
|
Phase 4 | |
| Completed |
NCT02290080 -
Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
|
Phase 3 | |
| Completed |
NCT02286544 -
Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT01405287 -
Study of Vascular Healing With the Combo Stent Versus the Everolimus Eluting Stent in ACS Patients by Means of OCT
|
Phase 2 | |
| Completed |
NCT00767507 -
Maintenance of Platelet Inhibition With Cangrelor
|
Phase 2 | |
| Completed |
NCT03672097 -
Prasugrel Switching Study in Patients With Acute Coronary Syndrome (ACS) Who Underwent Percutaneous Coronary Intervention (PCI)
|
Phase 4 | |
| Completed |
NCT00399880 -
Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes
|
N/A | |
| Completed |
NCT02430493 -
Evaluation on the Safety of Ticagrelor Among Chinese ACS Patients
|
N/A | |
| Completed |
NCT01994577 -
Optimum Troponin Cutoffs for ACS in the ED
|
||
| Completed |
NCT00313300 -
Safety Study of Apixaban in Recent Acute Coronary Syndrome
|
Phase 2 | |
| Completed |
NCT02244710 -
EndoTic - Endothelium and Ticagrelor
|
N/A | |
| Active, not recruiting |
NCT04090281 -
Implementing Precision Medicine Approaches to Guide Anti-platelet Selection
|
Phase 4 | |
| Active, not recruiting |
NCT03581578 -
VITROS Immunodiagnostic Products hs Troponin I
|
||
| Recruiting |
NCT04116931 -
OPTImal Management of Antithrombotic Agents: OPTIMA-5
|
Phase 4 | |
| Not yet recruiting |
NCT06449274 -
RESTORE Imaging: an OCT-IVUS Imaging Substudy of RESTORE Trial
|
N/A | |
| Completed |
NCT02171065 -
PROSPECT II & PROSPECT ABSORB - an Integrated Natural History Study and Randomized Trial.
|
N/A | |
| Completed |
NCT00855257 -
Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome
|
Phase 3 | |
| Completed |
NCT02733341 -
The Effect of IV Cangrelor and Oral Ticagrelor Study
|
Phase 4 | |
| Completed |
NCT02184884 -
Effect of Perioperative Clopidogrel Responsiveness on Ischemic Outcome in Patients With Acute Coronary Syndrome Undergoing Off-pump Coronary Artery Bypass Surgery
|