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Acute Aortic Dissection clinical trials

View clinical trials related to Acute Aortic Dissection.

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NCT ID: NCT04122573 Recruiting - Clinical trials for Acute Coronary Syndrome

Prospective Multicenter Study for Early Evaluation of Acute Chest Pain

PEACP
Start date: November 1, 2019
Phase:
Study type: Observational [Patient Registry]

In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital. To explore new biomarkers and screen clinical indicators with effective risk stratification and prognostic evaluation for ACP through proteomics technology and statistics methods. Risk stratification and short-term and long-term prognostic evaluation models for high-risk ACP will be established using large data analysis.

NCT ID: NCT03414866 Recruiting - Aortic Dissection Clinical Trials

Thoraflex Hybrid Post-Market Study

THOR
Start date: May 25, 2018
Phase:
Study type: Observational

This is a global, prospective non-interventional, multi-centre, post-market study of the Vascutek Thoraflex™ Hybrid system in patients with acute thoracic aortic syndrome, subacute/chronic dissection of the aorta and aortic aneurysm.

NCT ID: NCT03397251 Active, not recruiting - Clinical trials for Acute Aortic Dissection

Dissected Aorta Repair Through Stent Implantation (DARTS): A Feasibility, Safety and Performance Trial

DARTS
Start date: March 7, 2018
Phase: N/A
Study type: Interventional

This study is for participants who have been diagnosed with an acute aortic dissection/intramural hematoma (also known as a DeBakey I or Stanford type A dissection/ intramural hematoma). In a healthy aorta (the vessel that supplies blood to most of the body) the blood flows freely through the main lumen (a space inside the vessel where blood flows). The participants involved in this study have a tear that has separated the inner layer of the aorta wall and created a secondary channel (false lumen) in addition to the main channel (true lumen). The blood is now flowing through both channels.

NCT ID: NCT03381716 Completed - Clinical trials for Acute Aortic Dissection

Correlation Between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population

Start date: June 19, 2002
Phase: N/A
Study type: Observational

The study evaluated the prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex.

NCT ID: NCT02732340 Completed - Clinical trials for Acute Aortic Dissection

Triple-branch Stent Graft Placement for the Treatment of Acute DeBakey I Aortic Dissection

TBSGPT
Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate triple-branched stent placement in the treatment of acute DeBakey I aortic dissection . The investigators design a prospective, single-center, open-label, non-controlled clinical trial.

NCT ID: NCT02622750 Recruiting - Clinical trials for Acute Aortic Dissection

Triple-branch Stent Graft Placement and Total-arch Replacement for the Treatment of Acute DeBakey I Aortic Dissection

TBSGPATART
Start date: November 1, 2016
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to compare triple-branched stent placement with total-arch replacement in the treatment of acute DeBakey I aortic dissection . The investigators design optimal effect compare prospective, multi-center, randomized, open-label, parallel-group, non-inferiority clinical trial.

NCT ID: NCT01894334 Active, not recruiting - Clinical trials for Acute Aortic Dissection

Mechanism and Early Intervention Research on ALI During Emergence Surgery of Acute Stanford A Aortic Dissection

Start date: April 2013
Phase: N/A
Study type: Interventional

The morbidity rate of Stanford A type Acute Aortic Dissection(AAD) has been increasing, about 5-10/100,000* per year. Emergency surgery has been the main treatment for Acute Aortic Dissection, however perioperative mortality rate can be as high as 15~30%. Acute lung injury (ALI) is one of the main complications that happen during the perioperative period, which by itself covers 30%-50% of the overall mortality rate. Both domestic and foreign countries lack researches on risk factors, pathogenesis, disease progression and outcome of ALI, which happen during the perioperative period of Acute Aortic Dissection patients. This topic study follow projects in the preoperative of Acute Aortic Dissection'surgery 1. hemodynamic changes (aortic dissection resulting in acute aortic regurgitation, cardiac tamponade and proximal high blood pressure) 2. ischemia - reperfusion injury of aortic dissection distal organ 3. Aortic intima-media exposure cause coagulation / fibrinolytic system function disorder 4. systemic inflammatory response syndrome; use relevant clinical radiographic parameters, indicators of respiratory mechanics (oxygenation index and lung injury index) and biochemical indicators. To discuss risk factors and possible mechanisms of ADD patients with pre-operative ALI and observe their influences on the progress and prognosis of AAD, to explore early intervention in the preoperative for possible risk factors and mechanisms and to evaluate their influences on the prognosis, to achieve the purpose of reducing AAD perioperative mortality of ALI and medical expenses.