In Vitro Follicle Activation in Patient With Premature Ovarian Failure Under 36 Years Old

Activation of Primordial Follicles Clinical Trial

Official title: In Vitro Follicle Activation of Dormant Follicles in Patient With Premature Ovarian Failure Under 36 Years Old

Status Completed

Clinical Trial Summary

This is a clinical trial that the investigators aim to validate In-vitro Activation (IVA) treatment protocol, which was previously defined by Kazuhiro Kawamura (MD) and Aaron Hsueh (PhD), in Turkish patient with Premature Ovarian Insufficiency (POI) under age 36.

Clinical Trial Description

The objectives of the study is as following;

• Validation of the previously defined In-Vitro Activation Protocol approach in Turkish patients under 36 years old with Premature Ovarian Insufficiency (POI).

• Giving an opportunity to young POI patient in Turkey for having genetically own baby.

• Primary outcome measure would be live birth.

• For activation of primordial follicles, phosphatase and tensin homolog (PTEN) inhibitor and protein kinase B (AKT) stimulator will be used. ;

Related Conditions & MeSH terms

• Activation of Primordial Follicles
• Menopause, Premature
• Primary Ovarian Insufficiency

• NCT number: NCT04131244
• Study type: Interventional
• Source: Hacettepe University
• Status: Completed
• Phase: N/A
• Start date: December 1, 2017
• Completion date: December 15, 2019