View clinical trials related to Actinic Keratosis (AK).Filter by:
To compare the relative efficacy and safety and of 5-FU Cream to the marketed formulation Efudex® (5-FU) Cream, and to demonstrate the superior efficacy of the two active formulations over that of the Vehicle Control Cream, in the treatment of actinic keratosis.
Once or twice daily 12 week treatment in patients with Actinic Keratosis randomized to treatment in one of four arms.
This is a phase 4, multi-centre, randomized, two group, open label, active controlled, parallel group, 17 week trial.
The purpose of the study is to compare the risk of developing squamous skin cancer (SCC) or other types of cancer after treatment of AKs with ingenol mebutate gel or imiquimod cream. Subjects will be randomised to treatment with ingenol mebutate or imiquimod and will receive a second treatment cycle with the same treatment if the first treatment does not clear all AKs. Subjects will be followed over a period of three year (36 months) after first treatment