UCB Therapy in Acquired Brain Injury

Status Completed

Clinical Trial Summary

This open label trial is conducted to investigate the efficacy and safety of allogeneic umbilical cord blood (UCB) therapy for patients with acquired brain injury.

Clinical Trial Description

Acquired brain injury (ABI) means brain damage caused by events after birth, rather than as part of a genetic or congenital disorders. Those with ABI suffer from cognitive, physical, or behavioral impairments limiting their activity and participation in society. ABI results from traumatic or non-traumatic brain injury due to internal or external source (e.g. infection, brain tumor, hypoxia). Preclinical studies regarding cell therapy in animal models of ABI showed improvements of neurological dysfunction. UCB possess various stem or progenitor cells and is known to secrete neurotrophic factors to repair injured brain. This clinical research aims to determine the safety and efficacy of allogeneic UCB for patients with ABI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01885663
Study type	Interventional
Source	Bundang CHA Hospital
Contact
Status	Completed
Phase	Phase 1
Start date	June 2013
Completion date	September 2016

View Details

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