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Acne clinical trials

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NCT ID: NCT00964119 Terminated - Acne Clinical Trials

Musculoskeletal Effects of Isotretinoin During Acne Treatment in Pediatric Population

Start date: July 2008
Phase: N/A
Study type: Observational

This is a prospective study, that will follow participants over their course of treatment on Isotretinoin. All patients who are prescribed Isotretinoin for their acne treatment are registered in iPLEDGE. The iPLEDGE program involves a set of steps that the patient, physician and pharmacist must follow for the patient to take Isotretinoin. Patients will be asked if they are willing to participate in this research study to determine musculoskeletal changes in adolescents and young adults on systemic therapy using the highly sensitive magnetic resonance (MR) imaging modality. In addition to the MRI, participants will be asked if they are willing to give an extra sample of blood when their routine blood work is being done for iPLEDGE. This blood sample will be used to determine if there are any effects of isotretinoin on bone turnover markers.

NCT ID: NCT00939133 Completed - Acne Clinical Trials

Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin

Start date: July 2009
Phase: Phase 4
Study type: Interventional

The use of topical retinoids is a mainstay and basis of early acne treatment to prevent the progression to inflammatory lesions. Post oral isotretinoin, it is not uncommon for non-inflammatory papules and comedones to recur. However, there has been no formal study to look at the prevention of recurrence of these acne lesions post isotretinoin in a long term basis. This may enhance the therapeutic options for post isotretinoin patients in order to prevent recurrence of their disease. Hypothesis Tretinoin microsphere 0.04% will prevent recurrence of acne lesions.

NCT ID: NCT00913185 Completed - Acne Clinical Trials

Comparison Study of Topical Acne Regimens

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the effectiveness of two over the counter acne products in subjects with moderate severity acne vulgaris. The two products being compared in this study are Acne Free "Severe Acne Line" manufactured by University Medical Products, and Proactiv® manufactured by Guthy-Renker.

NCT ID: NCT00900939 Completed - Acne Clinical Trials

Plant-based Dietary Intervention for Treatment of Acne

Start date: July 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if a low-fat, vegan diet affects the number of acne lesions, acne severity, and acne extent.

NCT ID: NCT00883233 Completed - Acne Clinical Trials

Comparison of Four Different Regimens of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in Acne Vulgaris

FREE
Start date: April 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the tolerability of 3 treatment regimens containing Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel with that of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel standard daily overnight application for 12 weeks in the treatment of acne vulgaris. The efficacy of the four treatment regimens will also be evaluated.

NCT ID: NCT00841776 Completed - Acne Clinical Trials

Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne

Start date: August 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine the development of microbial resistance when using one of two topical acne therapies for the treatment of facial acne vulgaris.

NCT ID: NCT00837213 Completed - Acne Clinical Trials

Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne

Start date: August 2007
Phase: Phase 4
Study type: Interventional

To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne

NCT ID: NCT00833183 Completed - Acne Clinical Trials

Safety and Efficacy Study of Topical Methyaminlevulinate (MAL) in Subjects With Facial Acne

Start date: July 2007
Phase: Phase 2
Study type: Interventional

A study of safety and efficacy of topical methyaminlevulinate 80mg/g with and without occlusion followed by red light exposure in subjects with facial acne.

NCT ID: NCT00725439 Completed - Acne Clinical Trials

An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne

Start date: September 2004
Phase: Phase 2
Study type: Interventional

This study is looking at a new oral drug to treat acne. All patients in the study will get active drug, there is no placebo arm.

NCT ID: NCT00710489 Completed - Psoriasis Clinical Trials

Potential Research Study Participant Registry

Start date: May 2008
Phase:
Study type: Observational

The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment. The purpose of this study is also to assist current and future clinical trials with recruitment of subjects.