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Acne clinical trials

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NCT ID: NCT01206348 Completed - Acne Clinical Trials

Combination Treatment for Moderate to Severe Acne

Start date: September 2010
Phase: Phase 4
Study type: Interventional

To determine if a combination of three currently approved acne products are safe and effective for the treatment of moderate to severe acne

NCT ID: NCT01193764 Terminated - Acne Clinical Trials

Study Assessing the Effect of Chocolate Consumption in Subjects With A History of Acne Vulgaris

Start date: September 2010
Phase: N/A
Study type: Interventional

The investigators conducted a recent pilot study and found a strong positive correlation between the consumption of 100% chocolate and acne exacerbation. However, this study had limitations including the lack of placebo and the small sample size. Although studies have been conducted assessing chocolate's effect on acne, no study has been done evaluating this effect using chocolate with 100% cocoa content in a double blind placebo controlled fashion. This study will analyze the difference in the number and type of acneiform lesions per subject at the different time points (Day 4 and Day 7) compared to baseline in order to increase the validity of the investigators results. In addition, the investigators will use unsweetened cocoa powder,12 rather than chocolate candy, which contains higher quantities of additive ingredients such as sugar and milk to avoid interference with the results and the possibility to establish or not an association between the unsweetened cocoa and an effect on acne.

NCT ID: NCT01162837 Completed - Acne Clinical Trials

Safety & Effectiveness of the BEAM Device in Mild-to-moderate Acne

Start date: June 2010
Phase: N/A
Study type: Interventional

This study will determine if the use of the BEAM device reduces the signs and symptoms of mild-to-moderate acne.

NCT ID: NCT01138735 Completed - Acne Clinical Trials

Epiduo Pediatric Acne Study

Start date: June 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% administered once daily for up to 12 weeks in subjects 9 to 11 years of age with acne vulgaris.

NCT ID: NCT01135069 Completed - Acne Clinical Trials

Bioequivalence Study of Generic Tretinoin 0.1% Microsphere Gel, 0.1% Retin-A Micro® and Placebo

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The objective will be to assess clinical bioequivalence of 0.1% Retin-A Micro® Gel and Spear Pharmaceutical's generic 0.1% Tretinoin Microsphere Gel with a placebo arm.

NCT ID: NCT01111994 Active, not recruiting - Acne Clinical Trials

Efficacy & Safety of Clindamycin and Tretinoin in Acne

Start date: November 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is ascertain the efficacy and safety of Clindamycin Phosphate 1.2% and Tretinoin 0.025% in the treatment of Acne and Post Inflammatory Hyperpigmentation in patients with skin of color.

NCT ID: NCT01106807 Completed - Acne Clinical Trials

Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne

Start date: April 2010
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy of CD07223 1.5% Gel and 0.5% gel in reducing inflammatory, non-inflammatory, and total acne lesion counts after 6 weeks of twice daily applications. The study will also evaluate the safety of the study products using tolerance and adverse event data.

NCT ID: NCT01082523 Completed - Acne Clinical Trials

"A Randomized, Controlled, Evaluator-blinded Pilot Study to Evaluate the Effect of Automated Text Message Reminders on Patient Compliance With Topical Medications and Its Efficacy on Skin Disease Control in Adolescents and Adults With Mild to Moderate Acne"

Start date: February 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether an automated electronic reminder system using text messages sent to patient's cell phones will help patients with acne be more compliant with their topical medications and lead to an improvement of their acne. Hypothesis: Automatically delivered electronic reminders in the form of text messages will increase acne patient adherence to topical medications and consequently result in better treatment outcome and higher patient satisfaction

NCT ID: NCT01074502 Terminated - Acne Clinical Trials

Apremilast in the Treatment of Moderate to Severe Acne

Start date: February 2010
Phase: Phase 2
Study type: Interventional

Acne is a chronic inflammatory disease of the pilosebaceous unit that affects 80-90% of the population, especially teenagers, although adult acne is a significant problem for 3-6 % of adult men and 5-12% of adult women. Although acne is not a life-threatening disease, it produces significant psychological disturbances and permanent skin scars. A novel anti-inflammatory, not antibiotic drug may be an excellent alternative for the treatment of moderate to severe acne. Apremilast has been shown to inhibit the production of tumor necrosis factor (TNF)-alpha, IL-8 and neutrophil infiltration, all of which are elevated in inflammatory acne. Our intention is to study Apremilast in the treatment of moderate to severe acne.

NCT ID: NCT00998257 Completed - Contraception Clinical Trials

Regulatory Post Marketing Surveillance Study on YAZ

Start date: July 2009
Phase: N/A
Study type: Observational

The objective of this Post Marketing Surveillance (PMS) is to gain information about safety and efficacy in real practice.