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Acne Vulgaris clinical trials

View clinical trials related to Acne Vulgaris.

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NCT ID: NCT04555018 Completed - Acne Vulgaris Clinical Trials

Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

Start date: June 1, 2017
Phase:
Study type: Observational

The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. A cross sectional study was conducted with 50 samples, in June to October 2017.

NCT ID: NCT04548349 Completed - Healthy Clinical Trials

Profiling the Skin Microbiome in Response to Altreno in Acne Patients

Start date: April 23, 2021
Phase: Phase 4
Study type: Interventional

The study objective is to characterize the shift in the diversity and abundance of the skin microbial community at baseline and in response to Altreno monotherapy as compared to benzoyl peroxide (BPO) 2.5% leave-on gel monotherapy in acne patients.

NCT ID: NCT04538729 Completed - Acne Vulgaris Clinical Trials

Use of Alternative Therapy in Acne Vulgaris Patients

Start date: March 1, 2020
Phase:
Study type: Observational

Acne Vulgaris is a chronic skin disease. However, chronic and repetitive due to the quality of life and psychological status of patients can affect. Today, although the treatment is repetitive, chronic and requires follow-up due to the disease patients can turn to alternative and complementary medicine techniques. In recent years, studies on alternative medicine and complementary therapies have been noted in the medical literature. These studies also include Case Reports related to acne vulgaris. However, in our country, there is no study that tells us whether patients with acne vulgaris apply these treatments or not and what the practitioners think about the success of the treatment. The aim of the study will be to clarify issues such as whether patients with Acne Vulgaris apply alternative medicine and complementary therapies for their disease.

NCT ID: NCT04461366 Completed - Acne Atrophica Clinical Trials

Monopolar Radiofrequency Versus Pulsed Dye Laser for Treatment of Acne Scars

MRFPDL
Start date: January 15, 2019
Phase: N/A
Study type: Interventional

Background: The acne scar is a common disorder characterized by skin eruption or abnormalities on face, chest, and/or back in the adolescence which affect the cosmetic appearance. Purpose: The main aim of this study was to investigate whether monopolar radiofrequency (MRF) or pulsed dye laser (PDL) is more effective in the cases suffering from acne scars in the form of reducing acne scars and improving the cosmetic appearance.

NCT ID: NCT04451330 Completed - Acne Vulgaris Clinical Trials

A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)

DUAL
Start date: July 29, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study was to demonstrate that daily use of topical trifarotene (CD5789) 50 microgram per gram (mcg/g) cream when used in association with oral antibiotic is safe and effective for the treatment of severe AV.

NCT ID: NCT04367584 Completed - Acne Vulgaris Clinical Trials

Comparison of Malassezia Spp Proportions in Inflammatory and Non Inflammatory Facial Acne Vulgaris Lesions

Start date: October 1, 2018
Phase:
Study type: Observational

Acne vulgaris (AV) is a common inflammatory condition involving pilosebaceous unit. The pathogenesis of acne is multifactorial and skin microbiome is considered to be one of the key factors that aggravate inflammation. Malassezia spp is normal flora on the skin and several studies have reported its corelation with inflammatory AV lesion. Malassezia have higher lipase activity compared to Propionibacterium acnes which triggers an increase in free fatty acid and glycerol, the chemotactic factors towards neutrophils and inducing inflammation in AV. Malassezia folliculitis (MF) is sometimes confused with and may present together with AV. Pruritus usually presents in MF but some studies also reported itching as common symptom in AV. The objectives of this study were to identify the presence and the distribution of Malassezia spp. in facial AV lesions, to compare the distribution of Malassezia spp. between inflammatory and non-inflammatory lesions and to identify the association between Malassezia spp in acne lesions and pruritus symptom.

NCT ID: NCT04321070 Completed - Acne Vulgaris Clinical Trials

Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris

Start date: September 9, 2019
Phase: Phase 1
Study type: Interventional

Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris

NCT ID: NCT04301063 Completed - Acne Vulgaris Clinical Trials

Assess the Effects and the Tolerance of Cosmetic Product in the Follow-up Phase of Facial Acne for 1 Year

Start date: February 4, 2019
Phase:
Study type: Observational

Acne is a chronic inflammatory disease of the pilo-sebaceous unit in the skin. Indeed, your skin is covered with tiny holes called hair follicles, or pores. These pores contain sebaceous glands (also called oil glands) that make sebum, an oil that moistens your hair and skin. Most of the time, the glands make the right amount of sebum and the pores are fine. But sometimes a pore gets clogged up with too much sebum, dead skin cells, and germs called bacteria. This can cause acne. Pierre Fabre Laboratories have developed a cosmetic care product, a cream which is commercialized since September 2019. This leave-on skin care product is adapted for acne-prone skin. In this study, we are interested in the effects of this care product in facial acne evolution for 12 months (quality of life, acne severity, number of acne flares). Also, we are interested in the subject's satisfaction regarding the use of this care product. This study will also enable to know if the product is well tolerated in such application circumstances. This clinical study will be carried out in 54 subjects (female or male), aged between 12 and 35 years, in about 10 centers in different European countries. The maximal duration of the study for a subject will be 1 year. If you give your consent to take part in this study, you will receive a cosmetic care product, also called study product, that you will apply on your face twice a day (morning and evening) for the whole duration of the study. What makes this study original is the use of a smartphone application to help you to comply with the study procedures and to help the investigator to follow you.

NCT ID: NCT04300010 Completed - Acne Clinical Trials

Blue Light Therapy of C. Acnes

Start date: October 5, 2020
Phase: Phase 4
Study type: Interventional

This proposal aims to investigate a novel light-based treatment to reduce morbidity in shoulder surgical patients. This has potential to improve outcomes and reduce health care utilization associated with infectious complications of shoulder arthroplasty. Participants will be healthy male volunteers at least 18 years of age. They will be on study for approximately 2 days.

NCT ID: NCT04254601 Completed - Skin Diseases Clinical Trials

Laser Therapy Versus Narrow Band Ultraviolet B for the Treatment of Acne Vulgaris

LLLT-NBUB
Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Forty-five participants with facial AV were assigned randomly to three groups of fifteen subjects each. Each group received various therapies. Group A (Study group A) had received both NBUB and akne-Mycin; Group B( study group B) had received Red LLLT and akne-Mycin and group C (Control group) received only akne-Mycin cream. All 45 participants are tested at the initial treatments, after 4 weeks and after 8 weeks by the acne count, the intensity scale and the photographic test.