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Acne Rosacea clinical trials

View clinical trials related to Acne Rosacea.

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NCT ID: NCT04555525 Completed - Acne Rosacea Clinical Trials

A Pilot Study on the Use of Seysara for Rosacea

Start date: April 15, 2019
Phase: Phase 4
Study type: Interventional

This is a prospective, parallel group, randomized, investigator-blinded pilot study. Approximately 100 subjects will be randomized at a 3:1 ratio to Seysara (sarecycline) at a weight-based dose per label or Centrum Adult Multivitamin to take by mouth daily. The study is comprised of 5 visits: screening, baseline, week 4, week 8, and week 12. Investigators will perform rosacea IGA (Investigator Global Assessment,) inflammatory lesion count, record adverse events and con meds, and ask each subject to complete a DLQI (Dermatology Life Quality Index.)

NCT ID: NCT04214483 Recruiting - Acne Vulgaris Clinical Trials

A Pilot Study to Explore the Role of Gut Flora in Acne

Start date: March 2, 2020
Phase:
Study type: Observational

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

NCT ID: NCT03064438 Active, not recruiting - Acne Rosacea Clinical Trials

Efficacy of ACU-D1 in the Treatment of Acne Rosacea

Start date: November 28, 2017
Phase: Phase 2
Study type: Interventional

The study evaluates the safety, efficacy and tolerability of ACCU-D1 when applied twice daily for 12 weeks in adult patients with moderate to severe acne rosacea. Two thirds of participants will receive ACCU-D1 while one third will receive vehicle control.

NCT ID: NCT03003104 Completed - Acne Rosacea Clinical Trials

DMT210 Topical Gel in the Treatment of Acne Rosacea

Start date: January 2017
Phase: Phase 2
Study type: Interventional

The study evaluates the safety, tolerability, and efficacy of DMT210 Gel, 5% when applied twice daily for 12 weeks in adult patients with moderate to severe acne rosacea. Half of participants will receive DMT210 Gel while the other half will receive vehicle control.

NCT ID: NCT02270411 Recruiting - Atopic Dermatitis Clinical Trials

Inflammatory Cells From Various Pathologies

Start date: May 2014
Phase:
Study type: Observational

The objective of this experiment is to develop and validate in vitro methods to isolate inflammatory cells from skin biopsies for quantitative flow cytometry analysis. Real-time polymerase chain reaction (RT-PCR) will also be performed using skin biopsy samples to validate flow cytometry results. Such methods could eventually be used to better understand the pathophysiology and the mechanism of action of various medications in patients with atopic dermatitis, acne rosacea or vulgaris, HS, and systemic sclerosis. In this study, up to 15 healthy volunteers, 50 patients with atopic dermatitis, 15 patients with acne rosacea, 15 patients with psoriasis (to be used as control), 15 patients with acne vulgaris, 10 patients with psoriasis to develop a method of analysis for systemic sclerosis, and 10 patients with HS will be recruited. For the healthy volunteers, atopic dermatitis, psoriasis and HS groups, at least one (1) and a maximum of four (4) skin biopsies (4-5 mm) per subject will be performed. Biopsies will be performed on either the trunk or the limbs, excluding the hands and the feet. At least one (1) and a maximum of three (3) skin biopsies (2-3 mm) per subject will be collected for the acne rosacea and acne vulgaris groups from one or more body location(s) affected by the pathology. For patients with atopic dermatitis, an optional blood draw of up to 10 mL will be collected to measure serum IgE levels. For patients with atopic dermatitis, psoriasis, and HS, an optional blood collection of up to 50 mL will be collected to perform flow cytometry on circulating blood cells to study differences in flow cytometry results between cells extracted from biopsies and circulating cells.

NCT ID: NCT02147691 Completed - Acne Rosacea Clinical Trials

Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study

Start date: May 2014
Phase: Phase 4
Study type: Interventional

The pilot study will investigate whether combination treatment of Finacea 15% Gel and Brimonidine 0.33% Gel could be more effective than Brimonidine 0.33% Gel monotherapy in treating both the papules/pustules and erythema associated with rosacea.

NCT ID: NCT00580723 Completed - Acne Rosacea Clinical Trials

Effects of PRK 124 Lotion in Acne Rosacea

Start date: April 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this open-label study is to determine the tolerance and efficacy of twice-daily application of PRK 124 (Pyratine-6)(0.125%) moisturizing lotion for improving the signs and symptoms of mild to moderate facial rosacea.

NCT ID: NCT00041977 Completed - Acne Rosacea Clinical Trials

Determine the Effect of Administering Periostat(R) Twice Daily on Patients With Acne Rosacea

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Periostat(R), Doxycycline Hyclate 20 mg Tablets, taken twice daily is effective in reducing the red and white heads and overall redness associated with rosacea.