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ACL Tear clinical trials

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NCT ID: NCT04682392 Recruiting - ACL Tear Clinical Trials

ACL Bone Health and Loading Study

ACLBONE
Start date: February 17, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health. Hypothesis: The BFR group will have decreased bone mineral loss and improved functional performance compared to control group.

NCT ID: NCT04550299 Recruiting - Knee Injuries Clinical Trials

ACL Reconstruction With Simple and Double Bundle Technique Using Two Different Implants for Graft Fixation

Start date: February 26, 2013
Phase: N/A
Study type: Interventional

In this study our objective is to compare two tibial ACL graft fixation systems in patients undergoing two different reconstructions technique (with simple and double bundle) in terms of tendon graft osteointegration, functionality and return to sports.

NCT ID: NCT04536103 Recruiting - Osteoarthritis Clinical Trials

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

MVMS_MRI
Start date: April 1, 2022
Phase:
Study type: Observational

Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many challenges remain to clinically applying these techniques, including lack of standardized acquisition and quantification methods, and long acquisition times. The study aims to develop novel, fast and reproducible MR T1ρ and T2 relaxation time imaging methods on MR systems from multiple vendors and establish a platform for standardization and cross validation of these measures as a tool for clinical trials using such techniques. Following method validation, patients at risk for osteoarthritis will be tested.

NCT ID: NCT04058574 Recruiting - ACL Tear Clinical Trials

Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction

PRO-ACL
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This prospectively study aims to evaluate the evolution of knee joint proprioception on isokinetic dynamometer before and after Anterior Cruciate Ligament (ACL) reconstruction and its relationships with muscle strength, self reported questionnaire and return to sport. This study will include 30 athletes with isolated ACL rupture, and treated with ACL reconstruction surgery and 15 healthy volunteers.