The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament

Status Not yet recruiting

Clinical Trial Summary

The aim of our study is to evaluate the effect of accelerated rehabilitation post ACL reconstruction with and without augmentation on graft healing and return to normal activity clinically by scoring system and radiologically.

Clinical Trial Description

ACL reconstruction is the most commonly performed knee ligament reconstruction and employs a variety of surgical techniques. However, despite high success rates, it is still challenged by residual laxity and graft rupture. While the majority of patients who undergo ACLR will have good to excellent results, a subset of patients is at a higher risk for graft failure. For those that require revision surgery, the second operation often fails. Anterior cruciate ligament injuries account for 50% of knee ligament injuries for high school-aged adults. The most commonly used autografts for ACLR are the hamstring tendons (HT) and the bone-patellar tendon-bone (BPTB). However, questions remain about how patients with either an HT or a BPTB autograft recover knee muscle strength postoperatively. To help address and prevent future ACL failures, new repair and reconstruction techniques have been employed that incorporate suture augmentation. The goal of augmentation is to protect the newly repaired or reconstructed ligament during rehabilitation. Despite advances in anterior cruciate ligament (ACL) reconstruction surgical techniques and rehabilitation, recent studies report that between 20% to 50% of those with ACL reconstruction do not return to the same sports after surgery and 10% to 70% of those who resume preinjury sports participate at a reduced level or with significant functional impairments. Anecdotal evidence from patient report and clinical observation suggests that an inability to return to sports after ACL reconstruction can be partially attributed to a fear of reinjuring the knee. ;

Study Design

Related Conditions & MeSH terms

ACL Injury
Anterior Cruciate Ligament Injuries

Clinical Trial Details

NCT number	NCT05270551
Study type	Interventional
Source	Assiut University
Contact	Mohamed Abdel Tawab, Master
Phone	+201022141998
Email	mohamedtawab8892@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	March 1, 2022
Completion date	May 2023

View Details

See also
Status	Clinical Trial	Phase
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Withdrawn	`NCT03389685` - Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury	Phase 2
Recruiting	`NCT04958733` - Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study	N/A
Terminated	`NCT04101682` - Continuous Vs Single Shot Block After ACL	Early Phase 1
Not yet recruiting	`NCT05374382` - A Prehab Strengthening Program Prior to ACL Surgery on Lower Limb Structure and Function	N/A
Not yet recruiting	`NCT04068701` - Real-time Sensorimotor Feedback for Injury Prevention in Males Assessed in Virtual Reality	N/A
Recruiting	`NCT03479775` - Muscle Function and Traumatic Knee Injury in Sports
Not yet recruiting	`NCT05498285` - Post-ACL Reconstruction Rehab UPSCALER App RCT HPUPM	N/A
Recruiting	`NCT05461625` - ACL Reconstruction With/Without ALL Reconstruction	N/A
Active, not recruiting	`NCT03491046` - Molecular Imaging Assessment of ACL Viability	N/A
Withdrawn	`NCT04342000` - The Effect of Movement Education on Jumping/Landing Quality in High School Athletes	N/A
Completed	`NCT04993339` - Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound	Phase 3
Withdrawn	`NCT03614351` - Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery	N/A
Withdrawn	`NCT03670550` - Dynamic ACL Brace: In Vivo Kinematics	N/A
Recruiting	`NCT06206200` - The Effect of Cognitive Dual-task Rehabilitation on Arthrogenic Muscle Responses After ACL Reconstruction	N/A
Active, not recruiting	`NCT06167343` - Comparison of Semitendinosus and Quadriceps Grafts for Anterior Cruciate Ligament Reconstruction	N/A
Completed	`NCT04541940` - TeleRehabilitation Following ACL Reconstruction	N/A
Terminated	`NCT03497780` - Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:
Completed	`NCT04967937` - Neuromuscular Training Improves Single-Limb Stability	N/A
Recruiting	`NCT04901858` - Knee Aspiration and High Definition MRI for ACL Injury	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction With and Without Suture Tape Reinforcement

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms