The Effect of Whole Body Vibration After ACLR

ACL Injury Clinical Trial

Official title:

The Effect of Whole Body Vibration on Dynamic Knee Stability in Patients After Anterior Cruciate Ligament Reconstruction

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05254054
• Other study ID #: 2019.432
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2021
• Est. completion date: December 1, 2025

Study information

• Verified date: August 2023
• Source: Chinese University of Hong Kong
• Contact: Xin He, PhD
• Phone: 68102694
• Email: xinhe[@]cuhk.edu.hk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a randomised clinical trial to detect the effect of an 8-week whole body vibration training on muscle function and dynamic knee function during single leg squat and single leg hop in patients after anterior cruciate ligament reconstruction

Description:

In Hong Kong, over 3000 cases of ACL reconstruction are operated annually to restore knee stability. Despite recovery of knee passive laxity and muscle strength, dynamic knee stability is often not restored. The whole body vibration has been found to improve muscle strength, proprioception and balance after ACL reconstruction. This project will investigate the effect of whole body vibration on muscle elasticity, muscle coordination and landing knee biomechanics. It may provide useful evidence to the application of whole body vibration in improving dynamic knee stability, which will lead to a significant improvement in healthcare management for ACL patients . The current study serves to provide a clinical guideline for post-ACL reconstruction rehabilitation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: December 1, 2025
• Est. primary completion date: January 1, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

1. Aged 18-50;

2. Physically active before injury with Tegner score more than 6 (recreational/professional sport level);

3. Scheduled for ACLR because of sport injury;

4. Be able to walk with a pair of elbow crutches independently at 1 month after ACLR.

Exclusion Criteria:

1. Concomitant posterior cruciate ligament or lateral collateral ligament injury in the same knee;

2. Injury to the contralateral side;

3. Medical problems that are contradictory to WBV;

4. Prior experience of WBV to avoid any training or memory effect;

5. Women with pregnancy.

Related Conditions & MeSH terms

• ACL Injury
• Anterior Cruciate Ligament Injuries

Intervention

Other:
• whole body vibration
The whole body vibration is used when vibrations (mechanical oscillations) of a certain frequency are transferred to the human body. Humans are exposed to vibration through a contact surface that is in a mechanical vibrating state. It has been considered as an alternative and safe method for neuromuscular training and may be incorporated into current neuromuscular rehabilitation programs so as to enhance muscle recovery
• Conventional exercise training
A set of conventional exercises designed for ACL rehabilitation

Locations

Country	Name	City	State
Hong Kong	The chinese University of Hong Kong	Hong Kong

Sponsors (1)

Lead Sponsor	Collaborator
Chinese University of Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	knee flexion angle	Peak value of knee flexion will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
Primary	knee valgus angle	Peak value of knee valgus will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
Primary	knee internal rotation angle	Peak value of knee internal rotation will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
Primary	Vertical ground reaction force	Peak vertical ground reaction force will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention
Primary	Knee valgus torque	Peak knee valgus torque will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention
Primary	Knee extension torque	Peak knee extension torque will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention
Secondary	muscle strength	Isometric muscle strength of quadriceps and hamstring will be tested using an hand-held dynamometer. The isokinetic muscle strength of quadriceps and hamstring will be tested at 60°/s and 180°/s by the isokinetic dynamometer	immediately after intervention, three month after intervention
Secondary	muscle elasticity	Shear elastic modulus of vastus medialis, vastus lateralis, semimembranosus and biceps femoris will be assessed by shear wave elastography ultrasound.	immediately after intervention, three month after intervention
Secondary	muscle activation	Muscle activity level of vastus lateralis, vastus medialis, biceps femoris and semitendinosus will be assessed by electromyography	immediately after intervention, three month after intervention