Accident Caused by Snow Avalanche Clinical Trial
Official title:
Gas Diffusion in and Out of an Air Pocket After a Simulated Snow Avalanche and Its Impacts on Human Physiological Parameters.
The literature describes and report neurologic intact patients surviving an avalanche several hours after they were buried. The most important factor for surviving more than 15-35 min of burial is considered to be the presence of an air-filled space around the head and neck, termed an air pocket. Little is known how the inspired air is influenced by the patients breathing and how oxygen and carbon dioxide diffuse through snow.
In a controlled and simulated avalanche scenario the investigators want to investigate how
oxygen (O2) and carbon dioxide (CO2) diffuse and how rebreathing of CO2 in addition to mild
hypoxia influence standardized physiological parameters in two scenarios: Fresh air and no
fresh air delivered into the air pocket. The project is a field study designed to measure and
document gas diffusion through snow. The outcome measures are: (1) Concentration of O2 and
CO2 in the air pocket and 50 cm from the pocket. (2) Time interval for development of
threshold values for concentration of O2 and CO2. The investigators will also monitor
physiologic measures such as: Electrocardiogram (ECG), continuous invasive blood pressure,
cerebral oximetry, continuous pulse oximetry, transthoracic impedance, and gas content in
expired air. Subjective evaluation of comfort will also be scored. Twenty healthy young
volunteers with written consent to participate will be used as test subjects.
The study may have a clinical consequence for better outcome, for victims of avalanches by
providing additional air or oxygen close to the patient. We will also measure specific body
measures and spirometry.
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