Acanthosis Nigricans Clinical Trial
Official title:
Comparison Of The Outcome Of Treatment Of Topical 15% Trichloroacetic Acid Versus Topical 0.05% Tretinoin In The Treatment Of Acanthosis Nigricans
Verified date | August 2023 |
Source | Jinnah Postgraduate Medical Centre |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Acanthosis nigricans (AN) is a dermatosis with aesthetic implications and is characterized by the focal or diffuse development of a velvety, hyperpigmented cutaneous thickening in intertriginous areas. Trichloroacetic acid (TCA), a superficial chemical exfoliative agent has shown efficacy in treating acanthosis nigricans. Data from this would help in establishing it as a treatment of choice thereby lead to reduction in cost and benefit the patient both financially and psychologically.
Status | Completed |
Enrollment | 80 |
Est. completion date | June 20, 2023 |
Est. primary completion date | June 20, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 50 Years |
Eligibility | Inclusion Criteria: - Patients who will present with acanthosis nigricans as per operational definition will be included in the study. - Either gender. - Age 20-50 years. Exclusion Criteria: Pregnancy. - Breastfeeding. - Patients with history of skin resurfacing by dermabrasion, chemical peels and facial laser within the preceding 9 months. - Patients with history of hypersensitivity. - Malignant Acanthosis Nigricans. - Drug Induced Acanthosis Nigricans. |
Country | Name | City | State |
---|---|---|---|
Pakistan | JPMC | Karachi | Sindh |
Lead Sponsor | Collaborator |
---|---|
Jinnah Postgraduate Medical Centre |
Pakistan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | EFFICACY OF TOPICAL 15%TRICHLOROACETIC ACID VERSUS 0.05% TOPICAL TRETINOIN IN ACANTHOSIS NIGRICANS | Efficacy will be assessed by taking serials photographs before and after treatment shown efficacy in treating acanthosis nigricans. Data from this would help in establishing it as a treatment of choice thereby lead to reduction in cost and benefit the patient both financially and psychologically. | It will be assessed upto 02 months |
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