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Acanthamoeba Keratitis clinical trials

View clinical trials related to Acanthamoeba Keratitis.

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NCT ID: NCT03484507 Active, not recruiting - Clinical trials for Acanthamoeba Keratitis

Parasitic Ulcer Treatment Trial Pilot

Start date: January 1, 2018
Phase: Phase 2
Study type: Interventional

This is a study of optimal treatments for acanthamoeba keratitis. In the first part of the study, participants will be randomized to chlorhexidine monotherapy or chlorhexidine plus povidone iodine. After four weeks of therapy, participants will be re-randomized to early corticosteroids, later corticosteroids, or placebo.

NCT ID: NCT02506257 Active, not recruiting - Clinical trials for Acanthamoeba Keratitis

Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects

Start date: November 2015
Phase: Phase 1
Study type: Interventional

Randomized, double-masked, placebo-controlled, multiple center, parallel-group Phase 1 study to evaluate the safety and tolerability of 3 doses of preservative-free PHMB ophthalmic solution compared to placebo in healthy subjects