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Abortion, Therapeutic clinical trials

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NCT ID: NCT05182008 Recruiting - Clinical trials for Abortion in First Trimester

A Patient Decision Aid for Method of Early Abortion: A Randomized Control Trial

Start date: May 5, 2022
Phase: N/A
Study type: Interventional

Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion. When making a decision about which option is best for them, patient must consider their values as well as social resources and circumstances Patient decision aids (PtDAs) are tools to help patients make health-related decisions, particularly when no 'best' choice exist. Our research team has developed an online interactive patient decision aid on method of abortion based on international standards for decision aid development. We would like to investigate whether it leads to improved decisional quality in patients seeking early abortion. Methods: Phase 1 will be development of an abortion knowledge assessment tool. We will start by developing ten multiple choice questions based on information that is classically included in abortion education material. The goal is to ultimately include 5-7 well-performing questions in the trial. The ten questions will be sent to content experts to answer and rate. They will rate the questions on representativeness and importance. The questions will also be administered to community members without specific abortion knowledge. Results will be used to assess content validity and discriminator validity and revise the questionnaire. Phase 2 will be a randomized trial of people seeking abortion at less than 63 days gestation. Those who wish to participate will be randomized either the decision aid (study group) or the standard abortion clinic website (control). They will then be asked to participate in a survey immediately after they are finished reviewing the decision aid or website to. This survey will include questions about their decision, demographics, medical history, and their level of knowledge about abortion methods (by administering the knowledge assessment tool described above). The evaluation of the decision making will be measured using the Decisional Conflict Score. Four weeks post procedure, participants will be contacted by e-mail again and asked to complete a second survey identifying which type of abortion they underwent along with an inventory of perceived adverse treatment effects, as well as completing a Satisfaction with Decision Scale (SWD)

NCT ID: NCT02981030 Completed - Clinical trials for Abortion, Therapeutic

Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western Ukraine

Start date: November 23, 2016
Phase: Phase 4
Study type: Interventional

The study will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in Ukraine. The investigators intend to demonstrate the efficacy of oral administration of 200 mg mifepristone and buccal administration of 800 mcg misoprostol with gestations through 70 days, as well as the acceptability of this method.

NCT ID: NCT02037919 Completed - Contraception Clinical Trials

Nexplanon Application Post-Abortion (NAPA)

NAPA
Start date: June 2014
Phase: N/A
Study type: Interventional

Women who receive Nexplanon immediately post abortion will be significantly more likely to be using the device 6 months after the procedure than those assigned to receive the device 2-4 weeks after the procedure.

NCT ID: NCT00310921 Completed - Clinical trials for Abortion, Therapeutic

A Randomized Study of Cervical Priming With Misoprostol Prior to Elective First Trimester Pregnancy Termination

Start date: May 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether misoprostol administered prior to elective first trimester pregnancy has an effect on pain and ease of procedure and complications.