The Role of Hydrosalpinx in Recurrent Miscarriage

Status Completed

Clinical Trial Summary

Miscarriage affects one in five pregnancies and little progress has been made in understanding and treating this distressing condition. C. trachomatis is the most common sexually transmitted infection in the UK. C. trachomatis infection can have serious health consequences, including fallopian tube damage. Untreated C. trachomatis infection and tubal damage have been associated with miscarriage and adverse pregnancy outcomes such as preterm birth, low birth weight and stillbirth. A cohort study is needed to establish the prevalence of tubal disease in women with recurrent miscarriages. HyCoSy will be performed to identify tubal disease and establish the magnitude of the problem in the recurrent miscarriage population. The prognosis of tubal disease on miscarriage and other obstetric outcomes, and the role of medical interventions such as tubal surgery (to treat hydrosalpinx) on reducing miscarriage and adverse obstetric outcomes will also be studied. Objectives 1. Establish the prevalence of hydrosalpinx in the recurrent miscarriage population. 2. Establish the prognosis of women diagnosed with recurrent miscarriage with concurrent hydrosalpinx. 3. Explore the role of tubal surgery for improving reproductive outcomes in women with recurrent miscarriage population and hydrosalpinx.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03703401
Study type	Observational
Source	University of Birmingham
Contact
Status	Completed
Phase
Start date	February 28, 2018
Completion date	January 15, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05449171` - High Molecular Weight Hyaluronic Acid, α-lipoic Acid, Magnesium, Vitamin B6 and Vitamin D, in the Prevention of Spontaneous Abortion	N/A
Active, not recruiting	`NCT05896657` - Modulation of Reproductive Microbiota by Ligilactobacillus Salivarius CECT5713	N/A
Active, not recruiting	`NCT03736681` - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage	Phase 1
Completed	`NCT03636451` - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o	Phase 3
Completed	`NCT01335802` - Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Active, not recruiting	`NCT05516810` - The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles
Completed	`NCT04446572` - Application of Lactobacillus Salivarius CECT5713 in Infertility of Unknown Origin	Phase 2
Completed	`NCT01033903` - Optimal Treatment of Miscarriage	N/A
Withdrawn	`NCT02328742` - Development of a Bioabsorbable Medical Device for the Prevention of Postoperative Intra-uterine Adhesions.	N/A
Completed	`NCT01762098` - Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization	N/A
Active, not recruiting	`NCT04360564` - RPL: Interval to Live Birth and Adverse Perinatal Outcomes
Completed	`NCT04791020` - Topic Cervical Anesthesia Plus Paracervical Blockade for Pain Control During Endouterine Manual Aspiration	N/A
Recruiting	`NCT03220750` - University Hospital Advanced Age Pregnant Cohort	N/A
Completed	`NCT01904669` - Internet-based Study of Fertility and Early Pregnancy (PEEPS)	N/A
Not yet recruiting	`NCT00491270` - Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery	Phase 3
Active, not recruiting	`NCT02434900` - Vitamin D and Angiogenic Markers in Odense Child Cohort 1	N/A
Completed	`NCT01788540` - Intralipid for Recurrent Miscarriage	Phase 4
Recruiting	`NCT02633475` - Interleukin-10 Promoter-1082A/G Polymorphism and Idiopathic Recurrent Miscarriage Risk	N/A
Completed	`NCT02761772` - Early Pregnancy Cohort and Preimplantation Factor
Not yet recruiting	`NCT00256009` - Treatment of Late Abortion: Evacuatio Uteri or Conservative Treatment	Phase 4